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Index of Alpha/Theta Ratio of the Electroencephalogram: A New Marker for Alzheimer’s Disease

Overview of attention for article published in Frontiers in Aging Neuroscience, January 2013
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

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118 Mendeley
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Title
Index of Alpha/Theta Ratio of the Electroencephalogram: A New Marker for Alzheimer’s Disease
Published in
Frontiers in Aging Neuroscience, January 2013
DOI 10.3389/fnagi.2013.00060
Pubmed ID
Authors

Magali T. Schmidt, Paulo A. M. Kanda, Luis F. H. Basile, Helder Frederico da Silva Lopes, Regina Baratho, Jose L. C. Demario, Mario S. Jorge, Antonio E. Nardi, Sergio Machado, Jéssica N. Ianof, Ricardo Nitrini, Renato Anghinah

Abstract

Objective: We evaluated quantitative EEG measures to determine a screening index to discriminate Alzheimer's disease (AD) patients from normal individuals. Methods: Two groups of individuals older than 50 years, comprising a control group of 57 normal volunteers and a study group of 50 patients with probable AD, were compared. EEG recordings were obtained from subjects in a wake state with eyes closed at rest for 30 min. Logistic regression analysis was conducted. Results: Spectral potentials of the alpha and theta bands were computed for all electrodes and the alpha/theta ratio calculated. Logistic regression of alpha/theta of the mean potential of the C3 and O1 electrodes was carried out. A formula was calculated to aid the diagnosis of AD yielding 76.4% sensitivity and 84.6% specificity for AD with an area under the ROC curve of 0.92. Conclusion: Logistic regression of alpha/theta of the spectrum of the mean potential of EEG represents a good marker discriminating AD patients from normal controls.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Italy 1 <1%
Germany 1 <1%
Canada 1 <1%
Unknown 113 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 15%
Student > Ph. D. Student 17 14%
Researcher 17 14%
Professor 12 10%
Student > Master 7 6%
Other 22 19%
Unknown 25 21%
Readers by discipline Count As %
Neuroscience 16 14%
Engineering 15 13%
Medicine and Dentistry 15 13%
Psychology 11 9%
Computer Science 6 5%
Other 22 19%
Unknown 33 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2014.
All research outputs
#5,561,327
of 22,727,570 outputs
Outputs from Frontiers in Aging Neuroscience
#2,255
of 4,737 outputs
Outputs of similar age
#58,612
of 280,760 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#25
of 77 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,737 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,760 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.