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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Network-Based Biomarkers in Alzheimer’s Disease: Review and Future Directions
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, January 2014
|
| DOI | 10.3389/fnagi.2014.00012 |
| Pubmed ID | |
| Authors |
Jaime Gomez-Ramirez, Jinglong Wu |
| Abstract |
By 2050 it is estimated that the number of worldwide Alzheimer's disease (AD) patients will quadruple from the current number of 36 million people. To date, no single test, prior to postmortem examination, can confirm that a person suffers from AD. Therefore, there is a strong need for accurate and sensitive tools for the early diagnoses of AD. The complex etiology and multiple pathogenesis of AD call for a system-level understanding of the currently available biomarkers and the study of new biomarkers via network-based modeling of heterogeneous data types. In this review, we summarize recent research on the study of AD as a connectivity syndrome. We argue that a network-based approach in biomarker discovery will provide key insights to fully understand the network degeneration hypothesis (disease starts in specific network areas and progressively spreads to connected areas of the initial loci-networks) with a potential impact for early diagnosis and disease-modifying treatments. We introduce a new framework for the quantitative study of biomarkers that can help shorten the transition between academic research and clinical diagnosis in AD. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Estonia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 173 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Australia | 1 | <1% |
| Netherlands | 1 | <1% |
| Finland | 1 | <1% |
| Brazil | 1 | <1% |
| Spain | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 162 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 42 | 24% |
| Researcher | 26 | 15% |
| Student > Master | 25 | 14% |
| Student > Postgraduate | 12 | 7% |
| Student > Bachelor | 11 | 6% |
| Other | 32 | 18% |
| Unknown | 25 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 16% |
| Medicine and Dentistry | 27 | 16% |
| Neuroscience | 22 | 13% |
| Psychology | 15 | 9% |
| Computer Science | 9 | 5% |
| Other | 32 | 18% |
| Unknown | 40 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2014.
All research outputs
#17,691,590
of 22,745,803 outputs
Outputs from Frontiers in Aging Neuroscience
#3,776
of 4,745 outputs
Outputs of similar age
#220,138
of 305,224 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#12
of 16 outputs
Altmetric has tracked 22,745,803 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,745 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,224 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.