Title |
Regions of interest computed by SVM wrapped method for Alzheimer’s disease examination from segmented MRI
|
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Published in |
Frontiers in Aging Neuroscience, January 2014
|
DOI | 10.3389/fnagi.2014.00020 |
Pubmed ID | |
Authors |
Antonio R. Hidalgo-Muñoz, Javier Ramírez, Juan M. Górriz, Pablo Padilla |
Abstract |
Accurate identification of the most relevant brain regions linked to Alzheimer's disease (AD) is crucial in order to improve diagnosis techniques and to better understand this neurodegenerative process. For this purpose, statistical classification is suitable. In this work, a novel method based on support vector machine recursive feature elimination (SVM-RFE) is proposed to be applied on segmented brain MRI for detecting the most discriminant AD regions of interest (ROIs). The analyses are performed both on gray and white matter tissues, achieving up to 100% accuracy after classification and outperforming the results obtained by the standard t-test feature selection. The present method, applied on different subject sets, permits automatically determining high-resolution areas surrounding the hippocampal area without needing to divide the brain images according to any common template. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 33% |
Canada | 1 | 33% |
Spain | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 49 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 9 | 18% |
Researcher | 7 | 14% |
Student > Master | 7 | 14% |
Student > Postgraduate | 3 | 6% |
Student > Doctoral Student | 3 | 6% |
Other | 13 | 27% |
Unknown | 7 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Computer Science | 15 | 31% |
Engineering | 10 | 20% |
Medicine and Dentistry | 3 | 6% |
Agricultural and Biological Sciences | 2 | 4% |
Neuroscience | 2 | 4% |
Other | 8 | 16% |
Unknown | 9 | 18% |