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White matter microstructural organization and gait stability in older adults

Overview of attention for article published in Frontiers in Aging Neuroscience, June 2014
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Title
White matter microstructural organization and gait stability in older adults
Published in
Frontiers in Aging Neuroscience, June 2014
DOI 10.3389/fnagi.2014.00104
Pubmed ID
Authors

Sjoerd M. Bruijn, Annouchka Van Impe, Jacques Duysens, Stephan P. Swinnen

Abstract

Understanding age-related decline in gait stability and the role of alterations in brain structure is crucial. Here, we studied the relationship between white matter microstructural organization using Diffusion Tensor Imaging (DTI) and advanced gait stability measures in 15 healthy young adults (range 18-30 years) and 25 healthy older adults (range 62-82 years). Among the different gait stability measures, only stride time and the maximum Lyapunov exponent (which quantifies how well participants are able to attenuate small perturbations) were found to decline with age. White matter microstructural organization (FA) was lower throughout the brain in older adults. We found a strong correlation between FA in the left anterior thalamic radiation and left corticospinal tract on the one hand, and step width and safety margin (indicative of how close participants are to falling over) on the other. These findings suggest that white matter FA in tracts connecting subcortical and prefrontal areas is associated with the implementation of an effective stabilization strategy during gait.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Cuba 1 1%
Germany 1 1%
Unknown 97 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 20%
Student > Ph. D. Student 17 17%
Student > Master 17 17%
Student > Bachelor 8 8%
Student > Doctoral Student 6 6%
Other 12 12%
Unknown 20 20%
Readers by discipline Count As %
Neuroscience 18 18%
Medicine and Dentistry 15 15%
Engineering 8 8%
Sports and Recreations 8 8%
Agricultural and Biological Sciences 6 6%
Other 16 16%
Unknown 29 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2014.
All research outputs
#14,196,440
of 22,756,196 outputs
Outputs from Frontiers in Aging Neuroscience
#3,199
of 4,747 outputs
Outputs of similar age
#120,149
of 229,148 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#36
of 60 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,747 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,148 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.