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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The potential applications of Apolipoprotein E in personalized medicine
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, July 2014
|
| DOI | 10.3389/fnagi.2014.00154 |
| Pubmed ID | |
| Authors |
Sylvia Villeneuve, Diane Brisson, Natalie L. Marchant, Daniel Gaudet |
| Abstract |
Personalized medicine uses various individual characteristics to guide medical decisions. Apolipoprotein (ApoE), the most studied polymorphism in humans, has been associated with several diseases. The purpose of this review is to elucidate the potential role of ApoE polymorphisms in personalized medicine, with a specific focus on neurodegenerative diseases, by giving an overview of its influence on disease risk assessment, diagnosis, prognosis, and therapy. This review is not a systematic inventory of the literature, but rather a summary and discussion of novel, influential and promising works in the field of ApoE research that could be valuable for personalized medicine. Empirical evidence suggests that ApoE genotype informs pre-symptomatic risk for a wide variety of diseases, is valuable for the diagnosis of type III dysbetalipoproteinemia, increases risk of dementia in neurodegenerative diseases, and is associated with a poor prognosis following acute brain damage. ApoE status appears to influence the efficacy of certain drugs, outcome of clinical trials, and might also give insight into disease prevention. Assessing ApoE genotype might therefore help to guide medical decisions in clinical practice. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| France | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Brazil | 1 | <1% |
| Unknown | 109 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 17% |
| Student > Master | 18 | 16% |
| Student > Bachelor | 15 | 13% |
| Student > Ph. D. Student | 14 | 13% |
| Other | 9 | 8% |
| Other | 22 | 20% |
| Unknown | 15 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 20% |
| Biochemistry, Genetics and Molecular Biology | 18 | 16% |
| Medicine and Dentistry | 16 | 14% |
| Psychology | 12 | 11% |
| Neuroscience | 10 | 9% |
| Other | 15 | 13% |
| Unknown | 19 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2015.
All research outputs
#14,573,450
of 23,340,595 outputs
Outputs from Frontiers in Aging Neuroscience
#3,328
of 4,927 outputs
Outputs of similar age
#119,281
of 227,141 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#39
of 66 outputs
Altmetric has tracked 23,340,595 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,927 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,141 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.