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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, August 2014
|
| DOI | 10.3389/fnagi.2014.00208 |
| Pubmed ID | |
| Authors |
Marta Gonzalez-Freire, Rafael de Cabo, Stephanie A. Studenski, Luigi Ferrucci |
| Abstract |
Aging is associated with a progressive loss of muscle mass and strength and a decline in neurophysiological functions. Age-related neuromuscular junction (NMJ) plays a key role in musculoskeletal impairment that occurs with aging. However, whether changes in the NMJ precede or follow the decline of muscle mass and strength remains unresolved. Many factors such as mitochondrial dysfunction, oxidative stress, inflammation, changes in the innervation of muscle fibers, and mechanical properties of the motor units probably perform an important role in NMJ degeneration and muscle mass and strength decline in late life. This review addresses the primary events that might lead to NMJ dysfunction with aging, including studies on biomarkers, signaling pathways, and animal models. Interventions such as caloric restriction and exercise may positively affect the NMJ through this mechanism and attenuate the age-related progressive impairment in motor function. |
X Demographics
The data shown below were collected from the profiles of 57 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 11 | 19% |
| United States | 8 | 14% |
| Australia | 5 | 9% |
| Chile | 3 | 5% |
| Mexico | 2 | 4% |
| Norway | 2 | 4% |
| Canada | 2 | 4% |
| Spain | 2 | 4% |
| India | 1 | 2% |
| Other | 7 | 12% |
| Unknown | 14 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 30 | 53% |
| Scientists | 19 | 33% |
| Practitioners (doctors, other healthcare professionals) | 6 | 11% |
| Unknown | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 497 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Australia | 1 | <1% |
| United Kingdom | 1 | <1% |
| Slovenia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 492 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 88 | 18% |
| Student > Master | 76 | 15% |
| Student > Bachelor | 60 | 12% |
| Researcher | 52 | 10% |
| Student > Doctoral Student | 28 | 6% |
| Other | 65 | 13% |
| Unknown | 128 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 83 | 17% |
| Biochemistry, Genetics and Molecular Biology | 62 | 12% |
| Agricultural and Biological Sciences | 59 | 12% |
| Sports and Recreations | 39 | 8% |
| Nursing and Health Professions | 30 | 6% |
| Other | 83 | 17% |
| Unknown | 141 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 72. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2023.
All research outputs
#579,000
of 25,089,705 outputs
Outputs from Frontiers in Aging Neuroscience
#123
of 5,418 outputs
Outputs of similar age
#5,351
of 237,112 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#2
of 84 outputs
Altmetric has tracked 25,089,705 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,418 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,112 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.