Differences in cognitive aging: typology based on a community structure detection approach

Emi Saliasi, Linda Geerligs, Jelle R. Dalenberg, Monicque M. Lorist, Natasha M. Maurits

The current study investigated the extent and patterns of cognitive variability in younger and older adults. An important novelty of this study is the use of graph-based community structure detection analysis to map performance in a mixed population of 79 young and 76 older adults, without separating the age groups a-priori. We identified six subgroups, with distinct patterns of neuropsychological performance. The stability of the identified subgroups was confirmed by employing a cross-validation support vector machine based analysis. The majority of these subgroups comprised either young or older adults, confirming the expected role of aging in cognitive performance. In addition, we identified a subgroup of young and older adults who performed at a similar cognitive level of overall good cognitive performance with slightly decreased processing speed. This result showed that older age is not necessarily associated with general lower cognitive performance and that being young is not necessarily associated with superior cognitive performance. Moreover, cognitively better performing elderly had a significantly higher level of education attainment and higher crystallized intelligence than the other elderly, which suggests that older adults with higher cognitive reserve may be able to cope better with age-related neurobiological change.