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On the central role of brain connectivity in neurodegenerative disease progression

Overview of attention for article published in Frontiers in Aging Neuroscience, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

news
1 news outlet
twitter
6 X users
facebook
1 Facebook page

Citations

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54 Dimensions

Readers on

mendeley
133 Mendeley
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Title
On the central role of brain connectivity in neurodegenerative disease progression
Published in
Frontiers in Aging Neuroscience, May 2015
DOI 10.3389/fnagi.2015.00090
Pubmed ID
Authors

Yasser Iturria-Medina, Alan C. Evans

Abstract

Increased brain connectivity, in all its variants, is often considered an evolutionary advantage by mediating complex sensorimotor function and higher cognitive faculties. Interaction among components at all spatial scales, including genes, proteins, neurons, local neuronal circuits and macroscopic brain regions, are indispensable for such vital functions. However, a growing body of evidence suggests that, from the microscopic to the macroscopic levels, such connections might also be a conduit for in intra-brain disease spreading. For instance, cell-to-cell misfolded proteins (MP) transmission and neuronal toxicity are prominent connectivity-mediated factors in aging and neurodegeneration. This article offers an overview of connectivity dysfunctions associated with neurodegeneration, with a specific focus on how these may be central to both normal aging and the neuropathologic degenerative progression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Italy 1 <1%
Australia 1 <1%
Unknown 130 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 23%
Researcher 26 20%
Student > Master 13 10%
Student > Bachelor 10 8%
Other 9 7%
Other 23 17%
Unknown 21 16%
Readers by discipline Count As %
Neuroscience 38 29%
Agricultural and Biological Sciences 18 14%
Psychology 14 11%
Medicine and Dentistry 13 10%
Engineering 5 4%
Other 19 14%
Unknown 26 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2016.
All research outputs
#2,462,402
of 22,811,321 outputs
Outputs from Frontiers in Aging Neuroscience
#843
of 4,772 outputs
Outputs of similar age
#33,652
of 266,728 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#15
of 65 outputs
Altmetric has tracked 22,811,321 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,772 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,728 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.