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Mendeley readers
Attention Score in Context
| Title |
Hematopoietic cytokines as therapeutic players in early stages Parkinson’s disease
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, July 2015
|
| DOI | 10.3389/fnagi.2015.00126 |
| Pubmed ID | |
| Authors |
Kyle Farmer, Christopher Rudyk, Natalie A. Prowse, Shawn Hayley |
| Abstract |
Parkinson's disease (PD) is a devastating age related neurodegenerative disease that is believed to have a lengthy prodromal state. It is critical to find methods to harness compensatory recovery processes in order to slow or prevent the eventual progression of clinical symptoms. The current perspective paper argues that immune system signaling molecules represent such a promising therapeutic approach. Two cytokines of interest are granulocyte macrophage-colony stimulating factor (GM-CSF) and erythropoietin (EPO). These hematopoietic cytokines have been protective in models of stroke, neuronal injury, and more recently PD. It is our belief that these trophic cytokines can be used not only for cell protection but also regeneration. However, success is likely dependent on early intervention. This paper will outline our perspective on the development of novel trophic recovery treatments for PD. In particular, we present new data from our lab suggesting that EPO and GM-CSF can foster neural re-innervation in a "mild" or partial lesion PD model that could be envisioned as reflecting the early stages of the disease. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 24 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 25% |
| Researcher | 4 | 17% |
| Student > Bachelor | 2 | 8% |
| Other | 1 | 4% |
| Student > Doctoral Student | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 9 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 5 | 21% |
| Medicine and Dentistry | 4 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Agricultural and Biological Sciences | 1 | 4% |
| Other | 3 | 13% |
| Unknown | 8 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2015.
All research outputs
#2,819,763
of 22,816,807 outputs
Outputs from Frontiers in Aging Neuroscience
#1,208
of 4,773 outputs
Outputs of similar age
#37,419
of 262,956 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#26
of 67 outputs
Altmetric has tracked 22,816,807 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,773 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.