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Lifespan Extension Induced by Caffeine in Caenorhabditis elegans is Partially Dependent on Adenosine Signaling

Overview of attention for article published in Frontiers in Aging Neuroscience, December 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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9 X users
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1 Facebook page

Citations

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36 Dimensions

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58 Mendeley
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Title
Lifespan Extension Induced by Caffeine in Caenorhabditis elegans is Partially Dependent on Adenosine Signaling
Published in
Frontiers in Aging Neuroscience, December 2015
DOI 10.3389/fnagi.2015.00220
Pubmed ID
Authors

Jessika Cristina Bridi, Alexandre Guimarães de Almeida Barros, Letícia Reis Sampaio, Júlia Castro Damásio Ferreira, Felix Alexandre Antunes Soares, Marco Aurélio Romano-Silva

Abstract

Caffeine is a widely used psychoactive substance. Studies have shown that caffeine may play a protective role in aging-associated disorders. However, the mechanisms by which caffeine modulates aging are not yet clear. In this study, we have shown that caffeine increases Caenorhabditis elegans lifespan, delays its larval development, reduces reproduction and body length. These phenotypes were partly reversed by worm's exposure to adenosine, which suggest a putative common target. Moreover, they were dependent on a functional insulin/IGF-1-like pathway. Our results may shed light on new genetic determinants of aging.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 56 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Student > Bachelor 11 19%
Researcher 6 10%
Student > Master 5 9%
Student > Doctoral Student 3 5%
Other 5 9%
Unknown 14 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 28%
Biochemistry, Genetics and Molecular Biology 14 24%
Neuroscience 5 9%
Nursing and Health Professions 2 3%
Medicine and Dentistry 2 3%
Other 6 10%
Unknown 13 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2021.
All research outputs
#6,557,754
of 25,724,500 outputs
Outputs from Frontiers in Aging Neuroscience
#2,812
of 5,559 outputs
Outputs of similar age
#92,287
of 397,398 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#27
of 59 outputs
Altmetric has tracked 25,724,500 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 5,559 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,398 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.