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Mendeley readers
Attention Score in Context
| Title |
Progranulin Mutations Affects Brain Oscillatory Activity in Fronto-Temporal Dementia
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, February 2016
|
| DOI | 10.3389/fnagi.2016.00035 |
| Pubmed ID | |
| Authors |
Davide V. Moretti, Luisa Benussi, Silvia Fostinelli, Miriam Ciani, Giuliano Binetti, Roberta Ghidoni |
| Abstract |
Mild cognitive impairment (MCI) is a clinical stage indicating a prodromal phase of dementia. This practical concept could be used also for fronto-temporal dementia (FTD). Progranulin (PGRN) has been recently recognized as a useful diagnostic biomarker for fronto-temporal lobe degeneration (FTLD) due to GRN null mutations. Electroencephalography (EEG) is a reliable tool in detecting brain networks changes. The working hypothesis of the present study is that EEG oscillations could detect different modifications among FTLD stages (FTD-MCI versus overt FTD) as well as differences between GRN mutation carriers versus non-carriers in patients with overt FTD. EEG in all patients and PGRN dosage in patients with a clear FTD were detected. The cognitive state has been investigated through mini mental state examination (MMSE). MCI-FTD showed a significant lower spectral power in both alpha and theta oscillations as compared to overt FTD. GRN mutations carriers affected by FTLD show an increase in high alpha and decrease in theta oscillations as compared to non-carriers. EEG frequency rhythms are sensible to different stage of FTD and could detect changes in brain oscillatory activity affected by GRN mutations. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 50% |
| Switzerland | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 37 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 14% |
| Other | 4 | 11% |
| Student > Doctoral Student | 4 | 11% |
| Student > Ph. D. Student | 4 | 11% |
| Student > Bachelor | 2 | 5% |
| Other | 6 | 16% |
| Unknown | 12 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 16% |
| Neuroscience | 5 | 14% |
| Psychology | 4 | 11% |
| Agricultural and Biological Sciences | 2 | 5% |
| Veterinary Science and Veterinary Medicine | 1 | 3% |
| Other | 2 | 5% |
| Unknown | 17 | 46% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2016.
All research outputs
#3,127,191
of 22,852,911 outputs
Outputs from Frontiers in Aging Neuroscience
#1,611
of 4,798 outputs
Outputs of similar age
#51,611
of 297,592 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#31
of 77 outputs
Altmetric has tracked 22,852,911 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,798 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,592 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.