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Astrocytes As the Main Players in Primary Degenerative Disorders of the Human Central Nervous System

Overview of attention for article published in Frontiers in Aging Neuroscience, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
4 X users

Citations

dimensions_citation
26 Dimensions

Readers on

mendeley
73 Mendeley
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Title
Astrocytes As the Main Players in Primary Degenerative Disorders of the Human Central Nervous System
Published in
Frontiers in Aging Neuroscience, March 2016
DOI 10.3389/fnagi.2016.00045
Pubmed ID
Authors

Francisco Capani, Cecilia Quarracino, Roberto Caccuri, Roberto E. P. Sica

Abstract

Along the last years it has been demonstrated that non-neural cells play a major role in the pathogenesis of the primary degenerative disorders (PDDs) of the human central nervous system. Among them, astrocytes coordinate and participate in many different and complex metabolic processes, in close interaction with neurons. Moreover, increasing experimental evidence hints an early astrocytic dysfunction in these diseases. In this mini review we summarize the astrocytic behavior in PDDs, with special consideration to the experimental observations where astrocytic pathology precedes the development of neuronal dysfunction. We also suggest a different approach that could be consider in human investigations in Alzheimer's and Parkinson's disease. We believe that the study of PDDs with human brain samples may hold the key of a paradigmatic physiopathological process in which astrocytes might be the main players.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 3%
Switzerland 1 1%
Unknown 70 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Student > Master 11 15%
Student > Bachelor 11 15%
Researcher 10 14%
Professor 5 7%
Other 12 16%
Unknown 8 11%
Readers by discipline Count As %
Neuroscience 19 26%
Agricultural and Biological Sciences 17 23%
Medicine and Dentistry 9 12%
Biochemistry, Genetics and Molecular Biology 7 10%
Psychology 2 3%
Other 7 10%
Unknown 12 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2016.
All research outputs
#1,641,572
of 22,852,911 outputs
Outputs from Frontiers in Aging Neuroscience
#418
of 4,798 outputs
Outputs of similar age
#28,671
of 298,940 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#7
of 79 outputs
Altmetric has tracked 22,852,911 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,798 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,940 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.