↓ Skip to main content

White Matter Changes-Related Gait and Executive Function Deficits: Associations with Age and Parkinson's Disease

Overview of attention for article published in Frontiers in Aging Neuroscience, June 2017
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

news
1 news outlet
twitter
4 X users

Readers on

mendeley
87 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
White Matter Changes-Related Gait and Executive Function Deficits: Associations with Age and Parkinson's Disease
Published in
Frontiers in Aging Neuroscience, June 2017
DOI 10.3389/fnagi.2017.00213
Pubmed ID
Authors

Jennifer Sartor, Kristina Bettecken, Felix P. Bernhard, Marc Hofmann, Till Gladow, Tobias Lindig, Meltem Ciliz, Mara ten Kate, Johanna Geritz, Sebastian Heinzel, Marije Benedictus, Philip Scheltens, Markus A. Hobert, Walter Maetzler

Abstract

Background: White matter changes (WMC) are a common finding among older adults and patients with Parkinson's disease (PD), and have been associated with, e.g., gait deficits and executive dysfunction. How the factors age and PD influence WMC-related deficits is, to our best knowledge, not investigated to date. We hypothesized that advanced age and presence of PD leads to WMC-related symptoms while practicing tasks with a low complexity level, and low age and absence of PD leads to WMC-related symptoms while practicing tasks with a high complexity level. Methods: Hundred and thirty-eight participants [65 young persons without PD (50-69 years, yPn), 22 young PD patients (50-69 years, yPD), 36 old persons without PD (70-89 years, oPn) and 15 old PD patients (70-89 years, oPD)] were included. Presence and severity of WMC were determined with the modified Fazekas score. Velocity of walking under single and dual tasking conditions and the Trail Making Test (TMT) were used as gait and executive function parameters. Correlations between presence and severity of WMC, and gait and executive function parameters were tested in yPn, yPD, oPn, and oPD using Spearman's rank correlation, and significance between groups was evaluated with Fisher's z-transformed correlation coefficient. Results: yPn and yPD, as well as oPn and oPD did not differ regarding demographic and clinical parameters. Severity of WMC was not significantly different between groups. yPn and yPD displayed significant correlations of WMC with executive function parameters at low levels of task complexity, oPn at intermediate, and oPD at high complexity levels. Conclusion: This study argues for a relevant association of age and PD-related brain pathology with WMC-related gait and executive function deficits.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 87 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 15%
Student > Bachelor 10 11%
Student > Ph. D. Student 8 9%
Student > Doctoral Student 7 8%
Researcher 7 8%
Other 15 17%
Unknown 27 31%
Readers by discipline Count As %
Neuroscience 15 17%
Psychology 14 16%
Medicine and Dentistry 12 14%
Nursing and Health Professions 10 11%
Biochemistry, Genetics and Molecular Biology 3 3%
Other 5 6%
Unknown 28 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2017.
All research outputs
#2,799,592
of 22,985,065 outputs
Outputs from Frontiers in Aging Neuroscience
#1,138
of 4,833 outputs
Outputs of similar age
#53,641
of 314,551 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#46
of 131 outputs
Altmetric has tracked 22,985,065 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,833 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,551 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.