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Attention Score in Context
| Title |
Acupuncture Modulates the Cerebello-Thalamo-Cortical Circuit and Cognitive Brain Regions in Patients of Parkinson's Disease With Tremor
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, July 2018
|
| DOI | 10.3389/fnagi.2018.00206 |
| Pubmed ID | |
| Authors |
Zhe Li, Jun Chen, Jianbo Cheng, Sicong Huang, Yingyu Hu, Yijuan Wu, Guihua Li, Bo Liu, Xian Liu, Wenyuan Guo, Shuxuan Huang, Miaomiao Zhou, Xiang Chen, Yousheng Xiao, Chaojun Chen, Junbin Chen, Xiaodong Luo, Pingyi Xu |
| Abstract |
Objective: To investigate the effect of acupuncture on Parkinson's disease (PD) patients with tremor and its potential neuromechanism by functional magnetic resonance imaging (fMRI). Methods: Forty-one PD patients with tremor were randomly assigned to true acupuncture group (TAG, n = 14), sham acupuncture group (SAG, n = 14) and waiting group (WG, n = 13). All patients received levodopa for 12 weeks. Patients in TAG were acupunctured on DU20, GB20, and the Chorea-Tremor Controlled Zone, and patients in SAG accepted sham acupuncture, while patients in WG received no acupuncture treatment until 12 weeks after the course was ended. The UPDRS II and III subscales, and fMRI scans of the patients' brains were obtained before and after the treatment course. UPDRS II and III scores were analyzed by SPSS, while the degree centrality (DC), regional homogeneity (ReHo) and amplitude low-frequency fluctuation (ALFF) were determined by REST. Results: Acupuncture improved the UPDRS II and III scores in PD patients with tremor without placebo effect, only in tremor score. Acupuncture had specific effects on the cerebrocerebellar pathways as shown by the decreased DC and ReHo and increased ALFF values, and nonspecific effects on the spinocerebellar pathways as shown by the increased ReHo and ALFF values (P < 0.05, AlphaSim corrected). Increased ReHo values were observed within the thalamus and motor cortex of the PD patients (P < 0.05, AlphaSim corrected). In addition, the default mode network (DMN), visual areas and insula were activated by the acupuncture with increased DC, ReHo and/or ALFF, while the prefrontal cortex (PFC) presented a significant decrease in ReHo and ALFF values after acupuncture (P < 0.05, AlphaSim corrected). Conclusions: The cerebellum, thalamus and motor cortex, which are connected to the cerebello-thalamo-cortical (CTC) circuit, were modulated by the acupuncture stimulation to alleviate the PD tremor. The regulation of neural activity within the cognitive brain regions (the DMN, visual areas, insula and PFC) together with CTC circuit may contributes to enhancing movement and improving patients' daily life activities. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Congo, The Democratic Republic of the | 1 | 10% |
| Belgium | 1 | 10% |
| Philippines | 1 | 10% |
| United States | 1 | 10% |
| Spain | 1 | 10% |
| Canada | 1 | 10% |
| Brazil | 1 | 10% |
| Switzerland | 1 | 10% |
| Unknown | 2 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 60% |
| Scientists | 3 | 30% |
| Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 81 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 17% |
| Researcher | 9 | 11% |
| Student > Master | 8 | 10% |
| Student > Ph. D. Student | 6 | 7% |
| Other | 5 | 6% |
| Other | 10 | 12% |
| Unknown | 29 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 23% |
| Neuroscience | 10 | 12% |
| Nursing and Health Professions | 9 | 11% |
| Psychology | 8 | 10% |
| Business, Management and Accounting | 1 | 1% |
| Other | 4 | 5% |
| Unknown | 30 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2018.
All research outputs
#6,379,463
of 23,094,276 outputs
Outputs from Frontiers in Aging Neuroscience
#2,474
of 4,868 outputs
Outputs of similar age
#110,599
of 327,552 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#65
of 103 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 4,868 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,552 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.