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The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition

Overview of attention for article published in Frontiers in Neuroanatomy, January 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

blogs
1 blog

Citations

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37 Dimensions

Readers on

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84 Mendeley
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Title
The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition
Published in
Frontiers in Neuroanatomy, January 2011
DOI 10.3389/fnana.2011.00047
Pubmed ID
Authors

Christopher James Fitzpatrick, Paul J. Lombroso

Abstract

Striatal-enriched protein tyrosine phosphatase (STEP) has recently been implicated in several neuropsychiatric disorders with significant cognitive impairments, including Alzheimer's disease, schizophrenia, and fragile X syndrome. A model has emerged by which STEP normally opposes the development of synaptic strengthening and that disruption in STEP activity leads to aberrant synaptic function. We review the mechanisms by which STEP contributes to the etiology of these and other neuropsychiatric disorders. These findings suggest that disruptions in STEP activity may be a common mechanism for cognitive impairments in diverse illnesses.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Australia 1 1%
Unknown 82 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 26%
Student > Ph. D. Student 17 20%
Student > Bachelor 11 13%
Student > Master 10 12%
Professor > Associate Professor 5 6%
Other 9 11%
Unknown 10 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 30%
Neuroscience 16 19%
Biochemistry, Genetics and Molecular Biology 9 11%
Medicine and Dentistry 7 8%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Other 10 12%
Unknown 11 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2014.
All research outputs
#3,588,381
of 22,759,618 outputs
Outputs from Frontiers in Neuroanatomy
#277
of 1,159 outputs
Outputs of similar age
#23,747
of 180,570 outputs
Outputs of similar age from Frontiers in Neuroanatomy
#5
of 31 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,159 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,570 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.