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State-of-art neuroanatomical target analysis of high-definition and conventional tDCS montages used for migraine and pain control

Overview of attention for article published in Frontiers in Neuroanatomy, July 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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Title
State-of-art neuroanatomical target analysis of high-definition and conventional tDCS montages used for migraine and pain control
Published in
Frontiers in Neuroanatomy, July 2015
DOI 10.3389/fnana.2015.00089
Pubmed ID
Authors

Alexandre F. DaSilva, Dennis Q. Truong, Marcos F. DosSantos, Rebecca L. Toback, Abhishek Datta, Marom Bikson

Abstract

Although transcranial direct current stimulation (tDCS) studies promise to modulate cortical regions associated with pain, the electric current produced usually spreads beyond the area of the electrodes' placement. Using a forward-model analysis, this study compared the neuroanatomic location and strength of the predicted electric current peaks, at cortical and subcortical levels, induced by conventional and High-Definition-tDCS (HD-tDCS) montages developed for migraine and other chronic pain disorders. The electrodes were positioned in accordance with the 10-20 or 10-10 electroencephalogram (EEG) landmarks: motor cortex-supraorbital (M1-SO, anode and cathode over C3 and Fp2, respectively), dorsolateral prefrontal cortex (PFC) bilateral (DLPFC, anode over F3, cathode over F4), vertex-occipital cortex (anode over Cz and cathode over Oz), HD-tDCS 4 × 1 (one anode on C3, and four cathodes over Cz, F3, T7, and P3) and HD-tDCS 2 × 2 (two anodes over C3/C5 and two cathodes over FC3/FC5). M1-SO produced a large current flow in the PFC. Peaks of current flow also occurred in deeper brain structures, such as the cingulate cortex, insula, thalamus and brainstem. The same structures received significant amount of current with Cz-Oz and DLPFC tDCS. However, there were differences in the current flow to outer cortical regions. The visual cortex, cingulate and thalamus received the majority of the current flow with the Cz-Oz, while the anterior parts of the superior and middle frontal gyri displayed an intense amount of current with DLPFC montage. HD-tDCS montages enhanced the focality, producing peaks of current in subcortical areas at negligible levels. This study provides novel information regarding the neuroanatomical distribution and strength of the electric current using several tDCS montages applied for migraine and pain control. Such information may help clinicians and researchers in deciding the most appropriate tDCS montage to treat each pain disorder.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 2 <1%
Brazil 1 <1%
United Kingdom 1 <1%
Denmark 1 <1%
United States 1 <1%
Unknown 195 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 16%
Researcher 28 14%
Student > Master 27 13%
Student > Bachelor 22 11%
Student > Postgraduate 10 5%
Other 37 18%
Unknown 45 22%
Readers by discipline Count As %
Neuroscience 39 19%
Medicine and Dentistry 29 14%
Psychology 28 14%
Engineering 13 6%
Nursing and Health Professions 8 4%
Other 23 11%
Unknown 61 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2023.
All research outputs
#4,032,602
of 25,059,640 outputs
Outputs from Frontiers in Neuroanatomy
#289
of 1,246 outputs
Outputs of similar age
#47,486
of 268,156 outputs
Outputs of similar age from Frontiers in Neuroanatomy
#11
of 45 outputs
Altmetric has tracked 25,059,640 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,246 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,156 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.