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Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects

Overview of attention for article published in Frontiers in Neuroanatomy, December 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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Title
Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects
Published in
Frontiers in Neuroanatomy, December 2015
DOI 10.3389/fnana.2015.00160
Pubmed ID
Authors

Claire Cury, Roberto Toro, Fanny Cohen, Clara Fischer, Amel Mhaya, Jorge Samper-González, Dominique Hasboun, Jean-François Mangin, Tobias Banaschewski, Arun L. W. Bokde, Uli Bromberg, Christian Buechel, Anna Cattrell, Patricia Conrod, Herta Flor, Juergen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Hervé Lemaitre, Jean-Luc Martinot, Frauke Nees, Marie-Laure Paillère Martinot, Dimitri P. Orfanos, Tomas Paus, Luise Poustka, Michael N. Smolka, Henrik Walter, Robert Whelan, Vincent Frouin, Gunter Schumann, Joan A. Glaunès, Olivier Colliot, The IMAGEN Consortium

Abstract

The incomplete-hippocampal-inversion (IHI), also known as malrotation, is an atypical anatomical pattern of the hippocampus, which has been reported in healthy subjects in different studies. However, extensive characterization of IHI in a large sample has not yet been performed. Furthermore, it is unclear whether IHI are restricted to the medial-temporal lobe or are associated with more extensive anatomical changes. Here, we studied the characteristics of IHI in a community-based sample of 2008 subjects of the IMAGEN database and their association with extra-hippocampal anatomical variations. The presence of IHI was assessed on T1-weighted anatomical magnetic resonance imaging (MRI) using visual criteria. We assessed the association of IHI with other anatomical changes throughout the brain using automatic morphometry of cortical sulci. We found that IHI were much more frequent in the left hippocampus (left: 17%, right: 6%, χ(2)-test, p < 10(-28)). Compared to subjects without IHI, subjects with IHI displayed morphological changes in several sulci located mainly in the limbic lobe. Our results demonstrate that IHI are a common left-sided phenomenon in normal subjects and that they are associated with morphological changes outside the medial temporal lobe.

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The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
France 1 1%
Unknown 69 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 21%
Researcher 12 17%
Other 7 10%
Professor 6 8%
Lecturer 4 6%
Other 16 22%
Unknown 12 17%
Readers by discipline Count As %
Medicine and Dentistry 21 29%
Neuroscience 8 11%
Engineering 8 11%
Psychology 3 4%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 9 13%
Unknown 21 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2023.
All research outputs
#2,580,136
of 25,109,675 outputs
Outputs from Frontiers in Neuroanatomy
#130
of 1,249 outputs
Outputs of similar age
#42,588
of 402,505 outputs
Outputs of similar age from Frontiers in Neuroanatomy
#5
of 33 outputs
Altmetric has tracked 25,109,675 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,249 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 402,505 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.