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Cerebral Artery Diameter in Inbred Mice Varies as a Function of Strain

Overview of attention for article published in Frontiers in Neuroanatomy, February 2018
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Title
Cerebral Artery Diameter in Inbred Mice Varies as a Function of Strain
Published in
Frontiers in Neuroanatomy, February 2018
DOI 10.3389/fnana.2018.00010
Pubmed ID
Authors

Baogang Qian, Robert F. Rudy, Tianxi Cai, Rose Du

Abstract

Many strains of mice are utilized in mouse models of cerebrovascular diseases. Variations in vascular anatomy between these strains has been documented and may influence the phenotype in stroke models. To address inter-strain variations in the circle of Willis anatomy, the diameters of internal carotid, posterior communicating, anterior cerebral, and middle cerebral arteries in 144 mice from 32 inbred strains were measured. Arterial diameters were analyzed as a function of animal weight, age, and strain. Variations in the structure of the circle of Willis across strains were observed and noted. While right-sided anterior cerebral arteries were significantly greater in diameter than their left-sided counterparts across most strains, variations in arterial diameter are strain specific. Adult mouse weight was not found to be associated with arterial diameter across strains, suggesting that cerebral artery size is associated with strain independently of weight. This study demonstrates strain dependent variations in the murine circle of Willis, which should be taken into consideration when studying mouse models of cerebrovascular diseases.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 19%
Student > Master 7 15%
Other 4 9%
Researcher 4 9%
Student > Doctoral Student 3 6%
Other 5 11%
Unknown 15 32%
Readers by discipline Count As %
Neuroscience 7 15%
Agricultural and Biological Sciences 6 13%
Engineering 6 13%
Medicine and Dentistry 5 11%
Biochemistry, Genetics and Molecular Biology 3 6%
Other 4 9%
Unknown 16 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2019.
All research outputs
#14,968,843
of 23,025,074 outputs
Outputs from Frontiers in Neuroanatomy
#714
of 1,167 outputs
Outputs of similar age
#200,342
of 331,055 outputs
Outputs of similar age from Frontiers in Neuroanatomy
#21
of 33 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,167 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,055 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.