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Dopaminergic and Clinical Correlates of Pathological Gambling in Parkinson’s Disease: A Case Report

Overview of attention for article published in Frontiers in Behavioral Neuroscience, January 2013
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

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6 X users

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Title
Dopaminergic and Clinical Correlates of Pathological Gambling in Parkinson’s Disease: A Case Report
Published in
Frontiers in Behavioral Neuroscience, January 2013
DOI 10.3389/fnbeh.2013.00095
Pubmed ID
Authors

Mette Buhl Callesen, K. V. Hansen, A. Gjedde, J. Linnet, A. Møller

Abstract

Dopaminergic medication for motor symptoms in Parkinson's disease (PD) recently has been linked with impulse control disorders, including pathological gambling (PG), which affects up to 8% of patients. PG often is considered a behavioral addiction associated with disinhibition, risky decision-making, and altered striatal dopaminergic neurotransmission. Using [(11)C]raclopride with positron emission tomography, we assessed dopaminergic neurotransmission during Iowa Gambling Task performance. Here we present data from a single patient with PD and concomitant PG. We noted a marked decrease in [(11)C]raclopride binding in the left ventral striatum upon gambling, indicating a gambling-induced dopamine release. The results imply that PG in PD is associated with a high dose of dopaminergic medication, pronounced motor symptomatology, young age at disease onset, high propensity for sensation seeking, and risky decision-making. Overall, the findings are consistent with the hypothesis of medication-related PG in PD and underscore the importance of taking clinical variables, such as age and personality, into account when patients with PD are medicated, to reduce the risk of PG.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Germany 1 2%
Unknown 63 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 26%
Student > Master 10 15%
Researcher 6 9%
Other 6 9%
Student > Doctoral Student 3 5%
Other 10 15%
Unknown 13 20%
Readers by discipline Count As %
Psychology 26 40%
Medicine and Dentistry 7 11%
Neuroscience 6 9%
Agricultural and Biological Sciences 3 5%
Business, Management and Accounting 2 3%
Other 6 9%
Unknown 15 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2013.
All research outputs
#6,765,156
of 22,715,151 outputs
Outputs from Frontiers in Behavioral Neuroscience
#1,088
of 3,150 outputs
Outputs of similar age
#73,813
of 280,748 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#51
of 165 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 3,150 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.2. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,748 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 165 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.