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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Infusion of D1 Dopamine Receptor Agonist into Medial Frontal Cortex Disrupts Neural Correlates of Interval Timing
|
|---|---|
| Published in |
Frontiers in Behavioral Neuroscience, November 2015
|
| DOI | 10.3389/fnbeh.2015.00294 |
| Pubmed ID | |
| Authors |
Krystal L. Parker, Rafael N. Ruggiero, Nandakumar S. Narayanan |
| Abstract |
Medial frontal cortical (MFC) dopamine is essential for the organization of behavior in time. Our prior work indicates that blocking D1 dopamine receptors (D1DR) attenuates temporal processing and low-frequency oscillations by MFC neuronal networks. Here we investigate the effects of focal infusion of the D1DR agonist SKF82958 into MFC during interval timing. MFC D1DR agonist infusion impaired interval timing performance without changing overall firing rates of MFC neurons. MFC ramping patterns of neuronal activity that reflect temporal processing were attenuated following infusion of MFC D1DR agonist. MFC D1DR agonist infusion also altered MFC field potentials by enhancing delta activity between 1 and 4 Hz and attenuating alpha activity between 8 and 15 Hz. These data support the idea that the influence of D1-dopamine signals on frontal neuronal activity adheres to a U-shaped curve, and that cognition requires optimal levels of dopamine in frontal cortex. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 25% |
| United States | 1 | 13% |
| Canada | 1 | 13% |
| Switzerland | 1 | 13% |
| Unknown | 3 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 88% |
| Scientists | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 4% |
| Mexico | 1 | 2% |
| Germany | 1 | 2% |
| France | 1 | 2% |
| Unknown | 45 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 32% |
| Student > Ph. D. Student | 12 | 24% |
| Student > Postgraduate | 4 | 8% |
| Student > Master | 4 | 8% |
| Student > Bachelor | 3 | 6% |
| Other | 4 | 8% |
| Unknown | 7 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 16 | 32% |
| Psychology | 8 | 16% |
| Agricultural and Biological Sciences | 7 | 14% |
| Medicine and Dentistry | 4 | 8% |
| Computer Science | 1 | 2% |
| Other | 5 | 10% |
| Unknown | 9 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2015.
All research outputs
#6,242,478
of 22,832,057 outputs
Outputs from Frontiers in Behavioral Neuroscience
#989
of 3,171 outputs
Outputs of similar age
#78,179
of 282,783 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#28
of 95 outputs
Altmetric has tracked 22,832,057 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 3,171 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,783 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.