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Intellectual Profiles in KBG-Syndrome: A Wechsler Based Case-Control Study

Overview of attention for article published in Frontiers in Behavioral Neuroscience, December 2017
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Title
Intellectual Profiles in KBG-Syndrome: A Wechsler Based Case-Control Study
Published in
Frontiers in Behavioral Neuroscience, December 2017
DOI 10.3389/fnbeh.2017.00248
Pubmed ID
Authors

Linde C. M. van Dongen, Ellen Wingbermühle, Wouter Oomens, Anja G. Bos-Roubos, Charlotte W. Ockeloen, Tjitske Kleefstra, Jos I. M. Egger

Abstract

KBG syndrome is a neurodevelopmental disorder (NDD) caused by loss-of-function of the ANKRD11 gene. The core phenotype comprises developmental delay (DD)/ intellectual disability (ID) and several specific facial dysmorphisms. In addition, both ADHD- and ASD-related symptoms have been mentioned. For the correct understanding of these developmental and behavioral characteristics however, it is of great importance to apply objective measures, which seldom has been done in patients with KBG syndrome. In this study, intelligence profiles of patients with KBG syndrome (n = 18) were compared with a control group comprising patients with NDD caused by various other genetic defects (n = 17), by means of the Wechsler scales. These scales were also used to measure speed of information processing, working memory, verbal comprehension and perceptual reasoning. No significant differences were found in the global level of intelligence of patients with KBG syndrome as compared to the patient genetic control group. The same was true for Wechsler subtest results. Hence, behavioral problems associated with KBG syndrome cannot directly be related to or explained by a specific intelligence profile. Instead, specific assessment of neurocognitive functions should be performed to clarify the putative behavioral problems as observed in this syndrome.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 22%
Student > Bachelor 4 11%
Student > Doctoral Student 3 8%
Other 3 8%
Student > Ph. D. Student 3 8%
Other 6 16%
Unknown 10 27%
Readers by discipline Count As %
Psychology 9 24%
Medicine and Dentistry 6 16%
Neuroscience 6 16%
Social Sciences 2 5%
Biochemistry, Genetics and Molecular Biology 2 5%
Other 1 3%
Unknown 11 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2018.
All research outputs
#14,960,072
of 23,009,818 outputs
Outputs from Frontiers in Behavioral Neuroscience
#2,050
of 3,200 outputs
Outputs of similar age
#254,108
of 440,376 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#39
of 61 outputs
Altmetric has tracked 23,009,818 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,200 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.3. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,376 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.