↓ Skip to main content

Restoration of the striatal circuitry: from developmental aspects toward clinical applications

Overview of attention for article published in Frontiers in Cellular Neuroscience, January 2012
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

twitter
2 X users

Readers on

mendeley
63 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Restoration of the striatal circuitry: from developmental aspects toward clinical applications
Published in
Frontiers in Cellular Neuroscience, January 2012
DOI 10.3389/fncel.2012.00016
Pubmed ID
Authors

Marie-Christin Pauly, Tobias Piroth, Máté Döbrössy, Guido Nikkhah

Abstract

In the basal ganglia circuitry, the striatum is a highly complex structure coordinating motor and cognitive functions and it is severely affected in Huntington's disease (HD) patients. Transplantation of fetal ganglionic eminence (GE) derived precursor cells aims to restore neural circuitry in the degenerated striatum of HD patients. Pre-clinical transplantation in genetic and lesion HD animal models has increased our knowledge of graft vs. host interactions, and clinical studies have been shown to successfully reduce motor and cognitive effects caused by the disease. Investigating the molecular mechanisms of striatal neurogenesis is a key research target, since novel strategies aim on generating striatal neurons by differentiating embryonic stem cells or by reprogramming somatic cells as alternative cell source for neural transplantation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 3%
Unknown 61 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 24%
Student > Bachelor 12 19%
Researcher 8 13%
Other 5 8%
Student > Master 4 6%
Other 9 14%
Unknown 10 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 29%
Neuroscience 13 21%
Medicine and Dentistry 8 13%
Biochemistry, Genetics and Molecular Biology 7 11%
Environmental Science 1 2%
Other 6 10%
Unknown 10 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2012.
All research outputs
#13,669,726
of 22,675,759 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,968
of 4,202 outputs
Outputs of similar age
#150,077
of 244,088 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#11
of 42 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,202 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,088 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.