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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetic strategies to investigate neuronal circuit properties using stem cell-derived neurons
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, January 2012
|
| DOI | 10.3389/fncel.2012.00059 |
| Pubmed ID | |
| Authors |
Isabella Garcia, Cynthia Kim, Benjamin R. Arenkiel |
| Abstract |
The mammalian brain is anatomically and functionally complex, and prone to diverse forms of injury and neuropathology. Scientists have long strived to develop cell replacement therapies to repair damaged and diseased nervous tissue. However, this goal has remained unrealized for various reasons, including nascent knowledge of neuronal development, the inability to track and manipulate transplanted cells within complex neuronal networks, and host graft rejection. Recent advances in embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) technology, alongside novel genetic strategies to mark and manipulate stem cell-derived neurons, now provide unprecedented opportunities to investigate complex neuronal circuits in both healthy and diseased brains. Here, we review current technologies aimed at generating and manipulating neurons derived from ESCs and iPSCs toward investigation and manipulation of complex neuronal circuits, ultimately leading to the design and development of novel cell-based therapeutic approaches. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Australia | 1 | 2% |
| United Kingdom | 1 | 2% |
| Greece | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 48 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 23% |
| Student > Ph. D. Student | 10 | 19% |
| Student > Bachelor | 7 | 13% |
| Student > Master | 6 | 11% |
| Professor | 2 | 4% |
| Other | 6 | 11% |
| Unknown | 10 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 34% |
| Neuroscience | 8 | 15% |
| Medicine and Dentistry | 6 | 11% |
| Biochemistry, Genetics and Molecular Biology | 4 | 8% |
| Nursing and Health Professions | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 11 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 December 2012.
All research outputs
#18,325,190
of 22,691,736 outputs
Outputs from Frontiers in Cellular Neuroscience
#3,225
of 4,205 outputs
Outputs of similar age
#196,007
of 244,142 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#32
of 42 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,205 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,142 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.