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Differential regulation of neurexin at glutamatergic and GABAergic synapses

Overview of attention for article published in Frontiers in Cellular Neuroscience, January 2013
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2 X users

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17 Dimensions

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48 Mendeley
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Title
Differential regulation of neurexin at glutamatergic and GABAergic synapses
Published in
Frontiers in Cellular Neuroscience, January 2013
DOI 10.3389/fncel.2013.00035
Pubmed ID
Authors

Giulia Pregno, Elena Frola, Stefania Graziano, Annarita Patrizi, Federico Bussolino, Marco Arese, Marco Sassoè-Pognetto

Abstract

Neurexins (Nrxs) have emerged as potential determinants of synaptic specificity, but little is known about their localization at central synapses. Here we show that Nrxs have a remarkably selective localization at distinct types of glutamatergic synapses and we reveal an unexpected ontogenetic regulation of Nrx expression at GABAergic synapses. Our data indicate that synapses are specified by molecular interactions that involve both Nrx-dependent and Nrx-independent mechanisms. We propose that differences in the spatio-temporal profile of Nrx expression may contribute to specify the molecular identity of synapses.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Mexico 1 2%
Israel 1 2%
Belgium 1 2%
Unknown 44 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 25%
Researcher 12 25%
Student > Master 10 21%
Professor > Associate Professor 4 8%
Student > Bachelor 3 6%
Other 6 13%
Unknown 1 2%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 52%
Neuroscience 10 21%
Biochemistry, Genetics and Molecular Biology 3 6%
Chemistry 3 6%
Medicine and Dentistry 2 4%
Other 2 4%
Unknown 3 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2013.
All research outputs
#15,219,842
of 22,707,247 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,586
of 4,210 outputs
Outputs of similar age
#180,848
of 280,717 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#108
of 203 outputs
Altmetric has tracked 22,707,247 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,210 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,717 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 203 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.