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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Placental serotonin: implications for the developmental effects of SSRIs and maternal depression
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, January 2013
|
| DOI | 10.3389/fncel.2013.00047 |
| Pubmed ID | |
| Authors |
Juan C. Velasquez, Nick Goeden, Alexandre Bonnin |
| Abstract |
In addition to its role in the pathophysiology of numerous psychiatric disorders, increasing evidence points to serotonin (5-HT) as a crucial molecule for the modulation of neurodevelopmental processes. Recent evidence indicates that the placenta is involved in the synthesis of 5-HT from maternally derived tryptophan (TRP). This gives rise to the possibility that genetic and environmental perturbations directly affecting placental TRP metabolism may lead to abnormal brain circuit wiring in the developing embryo, and therefore contribute to the developmental origin of psychiatric disorders. In this review, we discuss how perturbations of the placental TRP metabolic pathway may lead to abnormal brain development and function throughout life. Of particular interest is prenatal exposure to maternal depression and antidepressants, both known to alter fetal development. We review existing evidence on how antidepressants can alter placental physiology in its key function of maintaining fetal homeostasis and have long-term effects on fetal forebrain development. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Poland | 2 | 18% |
| United States | 2 | 18% |
| Switzerland | 1 | 9% |
| Unknown | 6 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 91% |
| Scientists | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 3% |
| Netherlands | 2 | 1% |
| Croatia | 2 | 1% |
| Greece | 1 | <1% |
| Argentina | 1 | <1% |
| Unknown | 141 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 23% |
| Student > Master | 21 | 14% |
| Student > Bachelor | 21 | 14% |
| Researcher | 18 | 12% |
| Student > Doctoral Student | 10 | 7% |
| Other | 24 | 16% |
| Unknown | 23 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 31 | 20% |
| Neuroscience | 26 | 17% |
| Medicine and Dentistry | 25 | 16% |
| Psychology | 13 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 6% |
| Other | 19 | 13% |
| Unknown | 29 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2021.
All research outputs
#2,279,585
of 25,068,002 outputs
Outputs from Frontiers in Cellular Neuroscience
#322
of 4,645 outputs
Outputs of similar age
#21,926
of 293,389 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#9
of 203 outputs
Altmetric has tracked 25,068,002 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,645 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 293,389 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 203 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.