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Developmental origins of brain disorders: roles for dopamine

Overview of attention for article published in Frontiers in Cellular Neuroscience, January 2013
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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Title
Developmental origins of brain disorders: roles for dopamine
Published in
Frontiers in Cellular Neuroscience, January 2013
DOI 10.3389/fncel.2013.00260
Pubmed ID
Authors

Kelli M. Money, Gregg D. Stanwood

Abstract

Neurotransmitters and neuromodulators, such as dopamine, participate in a wide range of behavioral and cognitive functions in the adult brain, including movement, cognition, and reward. Dopamine-mediated signaling plays a fundamental neurodevelopmental role in forebrain differentiation and circuit formation. These developmental effects, such as modulation of neuronal migration and dendritic growth, occur before synaptogenesis and demonstrate novel roles for dopaminergic signaling beyond neuromodulation at the synapse. Pharmacologic and genetic disruptions demonstrate that these effects are brain region- and receptor subtype-specific. For example, the striatum and frontal cortex exhibit abnormal neuronal structure and function following prenatal disruption of dopamine receptor signaling. Alterations in these processes are implicated in the pathophysiology of neuropsychiatric disorders, and emerging studies of neurodevelopmental disruptions may shed light on the pathophysiology of abnormal neuronal circuitry in neuropsychiatric disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 346 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 3 <1%
United States 3 <1%
South Africa 2 <1%
Brazil 1 <1%
Finland 1 <1%
Sweden 1 <1%
Spain 1 <1%
United Kingdom 1 <1%
Unknown 333 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 68 20%
Student > Master 52 15%
Student > Bachelor 47 14%
Researcher 40 12%
Student > Doctoral Student 25 7%
Other 48 14%
Unknown 66 19%
Readers by discipline Count As %
Neuroscience 85 25%
Agricultural and Biological Sciences 79 23%
Medicine and Dentistry 26 8%
Biochemistry, Genetics and Molecular Biology 25 7%
Psychology 15 4%
Other 33 10%
Unknown 83 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2020.
All research outputs
#15,284,690
of 25,552,205 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,157
of 4,728 outputs
Outputs of similar age
#172,501
of 289,812 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#85
of 203 outputs
Altmetric has tracked 25,552,205 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,728 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,812 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 203 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.