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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Why looking at the whole hippocampus is not enough—a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer’s disease diagnosis
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, March 2014
|
| DOI | 10.3389/fncel.2014.00095 |
| Pubmed ID | |
| Authors |
Aleksandra Maruszak, Sandrine Thuret |
| Abstract |
The hippocampus is one of the earliest affected brain regions in Alzheimer's disease (AD) and its dysfunction is believed to underlie the core feature of the disease-memory impairment. Given that hippocampal volume is one of the best AD biomarkers, our review focuses on distinct subfields within the hippocampus, pinpointing regions that might enhance the predictive value of current diagnostic methods. Our review presents how changes in hippocampal volume, shape, symmetry and activation are reflected by cognitive impairment and how they are linked with neurogenesis alterations. Moreover, we revisit the functional differentiation along the anteroposterior longitudinal axis of the hippocampus and discuss its relevance for AD diagnosis. Finally, we indicate that apart from hippocampal subfield volumetry, the characteristic pattern of hippocampal hyperactivation associated with seizures and neurogenesis changes is another promising candidate for an early AD biomarker that could become also a target for early interventions. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 40% |
| Switzerland | 1 | 10% |
| France | 1 | 10% |
| United States | 1 | 10% |
| Canada | 1 | 10% |
| Unknown | 2 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 80% |
| Practitioners (doctors, other healthcare professionals) | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 228 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 226 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 54 | 24% |
| Researcher | 36 | 16% |
| Student > Master | 20 | 9% |
| Student > Bachelor | 16 | 7% |
| Student > Postgraduate | 11 | 5% |
| Other | 38 | 17% |
| Unknown | 53 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 45 | 20% |
| Psychology | 32 | 14% |
| Medicine and Dentistry | 24 | 11% |
| Agricultural and Biological Sciences | 20 | 9% |
| Biochemistry, Genetics and Molecular Biology | 13 | 6% |
| Other | 24 | 11% |
| Unknown | 70 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 79. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2022.
All research outputs
#460,689
of 23,041,514 outputs
Outputs from Frontiers in Cellular Neuroscience
#38
of 4,267 outputs
Outputs of similar age
#4,430
of 226,961 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#1
of 32 outputs
Altmetric has tracked 23,041,514 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,267 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,961 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.