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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Optimizing neuronal differentiation from induced pluripotent stem cells to model ASD
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, April 2014
|
| DOI | 10.3389/fncel.2014.00109 |
| Pubmed ID | |
| Authors |
Dae-Sung Kim, P. Joel Ross, Kirill Zaslavsky, James Ellis |
| Abstract |
Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder characterized by deficits in social communication, and restricted and repetitive patterns of behavior. Despite its high prevalence, discovery of pathophysiological mechanisms underlying ASD has lagged due to a lack of appropriate model systems. Recent advances in induced pluripotent stem cell (iPSC) technology and neural differentiation techniques allow for detailed functional analyses of neurons generated from living individuals with ASD. Refinement of cortical neuron differentiation methods from iPSCs will enable mechanistic studies of specific neuronal subpopulations that may be preferentially impaired in ASD. In this review, we summarize recent accomplishments in differentiation of cortical neurons from human pluripotent stems cells and efforts to establish in vitro model systems to study ASD using personalized neurons. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 270 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 1% |
| Brazil | 3 | 1% |
| United Kingdom | 3 | 1% |
| Portugal | 2 | <1% |
| Chile | 1 | <1% |
| Israel | 1 | <1% |
| Netherlands | 1 | <1% |
| Canada | 1 | <1% |
| Sweden | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 253 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 77 | 29% |
| Researcher | 49 | 18% |
| Student > Master | 41 | 15% |
| Student > Bachelor | 29 | 11% |
| Student > Doctoral Student | 13 | 5% |
| Other | 38 | 14% |
| Unknown | 23 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 97 | 36% |
| Neuroscience | 58 | 21% |
| Biochemistry, Genetics and Molecular Biology | 46 | 17% |
| Medicine and Dentistry | 14 | 5% |
| Engineering | 9 | 3% |
| Other | 21 | 8% |
| Unknown | 25 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2016.
All research outputs
#12,898,658
of 22,754,104 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,624
of 4,222 outputs
Outputs of similar age
#106,513
of 226,970 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#24
of 41 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,222 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,970 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.