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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Imaging of human differentiated 3D neural aggregates using light sheet fluorescence microscopy
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, August 2014
|
| DOI | 10.3389/fncel.2014.00221 |
| Pubmed ID | |
| Authors |
Emilio J. Gualda, Daniel Simão, Catarina Pinto, Paula M. Alves, Catarina Brito |
| Abstract |
The development of three dimensional (3D) cell cultures represents a big step for the better understanding of cell behavior and disease in a more natural like environment, providing not only single but multiple cell type interactions in a complex 3D matrix, highly resembling physiological conditions. Light sheet fluorescence microscopy (LSFM) is becoming an excellent tool for fast imaging of such 3D biological structures. We demonstrate the potential of this technique for the imaging of human differentiated 3D neural aggregates in fixed and live samples, namely calcium imaging and cell death processes, showing the power of imaging modality compared with traditional microscopy. The combination of light sheet microscopy and 3D neural cultures will open the door to more challenging experiments involving drug testing at large scale as well as a better understanding of relevant biological processes in a more realistic environment. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 25% |
| Canada | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Unknown | 118 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 31 | 26% |
| Student > Ph. D. Student | 23 | 19% |
| Student > Master | 15 | 13% |
| Student > Bachelor | 10 | 8% |
| Student > Doctoral Student | 7 | 6% |
| Other | 18 | 15% |
| Unknown | 16 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 21% |
| Biochemistry, Genetics and Molecular Biology | 19 | 16% |
| Engineering | 19 | 16% |
| Physics and Astronomy | 15 | 13% |
| Neuroscience | 6 | 5% |
| Other | 19 | 16% |
| Unknown | 17 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2018.
All research outputs
#7,113,434
of 22,764,165 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,320
of 4,227 outputs
Outputs of similar age
#69,430
of 230,333 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#16
of 62 outputs
Altmetric has tracked 22,764,165 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 4,227 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,333 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.