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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The impact of microglial activation on blood-brain barrier in brain diseases
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, November 2014
|
| DOI | 10.3389/fncel.2014.00362 |
| Pubmed ID | |
| Authors |
Anna Carolina Carvalho da Fonseca, Diana Matias, Celina Garcia, Rackele Amaral, Luiz Henrique Geraldo, Catarina Freitas, Flavia Regina Souza Lima |
| Abstract |
The blood-brain barrier (BBB), constituted by an extensive network of endothelial cells (ECs) together with neurons and glial cells, including microglia, forms the neurovascular unit (NVU). The crosstalk between these cells guarantees a proper environment for brain function. In this context, changes in the endothelium-microglia interactions are associated with a variety of inflammation-related diseases in brain, where BBB permeability is compromised. Increasing evidences indicate that activated microglia modulate expression of tight junctions, which are essential for BBB integrity and function. On the other hand, the endothelium can regulate the state of microglial activation. Here, we review recent advances that provide insights into interactions between the microglia and the vascular system in brain diseases such as infectious/inflammatory diseases, epilepsy, ischemic stroke and neurodegenerative disorders. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 581 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| Mexico | 2 | <1% |
| Netherlands | 1 | <1% |
| Portugal | 1 | <1% |
| Unknown | 575 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 132 | 23% |
| Researcher | 83 | 14% |
| Student > Master | 75 | 13% |
| Student > Bachelor | 61 | 10% |
| Student > Doctoral Student | 33 | 6% |
| Other | 87 | 15% |
| Unknown | 110 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 115 | 20% |
| Agricultural and Biological Sciences | 105 | 18% |
| Biochemistry, Genetics and Molecular Biology | 70 | 12% |
| Medicine and Dentistry | 66 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 25 | 4% |
| Other | 71 | 12% |
| Unknown | 129 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2021.
All research outputs
#4,736,879
of 23,203,401 outputs
Outputs from Frontiers in Cellular Neuroscience
#958
of 4,304 outputs
Outputs of similar age
#54,744
of 263,197 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#8
of 86 outputs
Altmetric has tracked 23,203,401 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,304 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,197 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.