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The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity

Overview of attention for article published in Frontiers in Cellular Neuroscience, November 2014
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  • Good Attention Score compared to outputs of the same age (76th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

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3 X users
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1 Facebook page
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1 Wikipedia page

Citations

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250 Dimensions

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623 Mendeley
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Title
The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
Published in
Frontiers in Cellular Neuroscience, November 2014
DOI 10.3389/fncel.2014.00401
Pubmed ID
Authors

Thomas E. Chater, Yukiko Goda

Abstract

In the mammalian central nervous system, excitatory glutamatergic synapses harness neurotransmission that is mediated by ion flow through α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). AMPARs, which are enriched in the postsynaptic membrane on dendritic spines, are highly dynamic, and shuttle in and out of synapses in an activity-dependent manner. Changes in their number, subunit composition, phosphorylation state, and accessory proteins can all regulate AMPARs and thus modify synaptic strength and support cellular forms of learning. Furthermore, dysregulation of AMPAR plasticity has been implicated in various pathological states and has important consequences for mental health. Here we focus on the mechanisms that control AMPAR plasticity, drawing particularly from the extensive studies on hippocampal synapses, and highlight recent advances in the field along with considerations for future directions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 623 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Netherlands 1 <1%
Korea, Republic of 1 <1%
Unknown 619 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 157 25%
Student > Master 92 15%
Student > Bachelor 84 13%
Researcher 65 10%
Student > Doctoral Student 30 5%
Other 62 10%
Unknown 133 21%
Readers by discipline Count As %
Neuroscience 204 33%
Agricultural and Biological Sciences 116 19%
Biochemistry, Genetics and Molecular Biology 64 10%
Medicine and Dentistry 27 4%
Pharmacology, Toxicology and Pharmaceutical Science 18 3%
Other 44 7%
Unknown 150 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2022.
All research outputs
#6,243,714
of 23,106,934 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,139
of 4,284 outputs
Outputs of similar age
#85,663
of 363,704 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#17
of 86 outputs
Altmetric has tracked 23,106,934 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 4,284 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 363,704 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.