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Structural homeostasis in the nervous system: a balancing act for wiring plasticity and stability

Overview of attention for article published in Frontiers in Cellular Neuroscience, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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153 Mendeley
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Title
Structural homeostasis in the nervous system: a balancing act for wiring plasticity and stability
Published in
Frontiers in Cellular Neuroscience, January 2015
DOI 10.3389/fncel.2014.00439
Pubmed ID
Authors

Jun Yin, Quan Yuan

Abstract

Experience-dependent modifications of neural circuits provide the cellular basis for functional adaptation and learning, while presenting significant challenges to the stability of neural networks. The nervous system copes with these perturbations through a variety of compensatory mechanisms with distinct spatial and temporal profiles. Mounting evidence suggests that structural plasticity, through modifications of the number and structure of synapses, or changes in local and long-range connectivity, might contribute to the stabilization of network activity and serve as an important component of the homeostatic regulation of the nervous system. Conceptually similar to the homeostatic regulation of synaptic strength and efficacy, homeostatic structural plasticity has a profound and lasting impact on the intrinsic excitability of the neuron and circuit properties, yet remains largely unexplored. In this review, we examine recent reports describing structural modifications associated with functional compensation in both developing and adult nervous systems, and discuss the potential role for structural homeostasis in maintaining network stability and its implications in physiological and pathological conditions of the nervous systems.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Netherlands 1 <1%
Peru 1 <1%
Canada 1 <1%
Unknown 148 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 22%
Researcher 24 16%
Student > Bachelor 21 14%
Student > Master 19 12%
Student > Doctoral Student 8 5%
Other 23 15%
Unknown 24 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 49 32%
Neuroscience 47 31%
Biochemistry, Genetics and Molecular Biology 11 7%
Medicine and Dentistry 7 5%
Psychology 5 3%
Other 11 7%
Unknown 23 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2016.
All research outputs
#3,565,461
of 22,787,797 outputs
Outputs from Frontiers in Cellular Neuroscience
#748
of 4,236 outputs
Outputs of similar age
#51,736
of 352,059 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#10
of 82 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,236 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,059 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.