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Elementary properties of Ca2+ channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses

Overview of attention for article published in Frontiers in Cellular Neuroscience, April 2015
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

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Title
Elementary properties of Ca2+ channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses
Published in
Frontiers in Cellular Neuroscience, April 2015
DOI 10.3389/fncel.2015.00123
Pubmed ID
Authors

Jacopo Magistretti, Paolo Spaiardi, Stuart L. Johnson, Sergio Masetto

Abstract

Voltage-gated calcium (Cav1.3) channels in mammalian inner hair cells (IHCs) open in response to sound and the resulting Ca(2+) entry triggers the release of the neurotransmitter glutamate onto afferent terminals. At low to mid sound frequencies cell depolarization follows the sound sinusoid and pulses of transmitter release from the hair cell generate excitatory postsynaptic currents (EPSCs) in the afferent fiber that translate into a phase-locked pattern of action potential activity. The present article summarizes our current understanding on the elementary properties of single IHC Ca(2+) channels, and how these could have functional implications for certain, poorly understood, features of synaptic transmission at auditory hair cell ribbon synapses.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 24%
Student > Bachelor 5 20%
Student > Ph. D. Student 4 16%
Student > Postgraduate 3 12%
Student > Doctoral Student 2 8%
Other 4 16%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 28%
Medicine and Dentistry 5 20%
Neuroscience 5 20%
Biochemistry, Genetics and Molecular Biology 3 12%
Physics and Astronomy 2 8%
Other 2 8%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2015.
All research outputs
#7,401,789
of 22,805,349 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,402
of 4,240 outputs
Outputs of similar age
#89,977
of 264,900 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#35
of 102 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 4,240 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,900 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 102 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.