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Interplay of environmental signals and progenitor diversity on fate specification of cortical GABAergic neurons

Overview of attention for article published in Frontiers in Cellular Neuroscience, April 2015
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Title
Interplay of environmental signals and progenitor diversity on fate specification of cortical GABAergic neurons
Published in
Frontiers in Cellular Neuroscience, April 2015
DOI 10.3389/fncel.2015.00149
Pubmed ID
Authors

Juliana A. Brandão, Rodrigo N. Romcy-Pereira

Abstract

Cortical GABAergic interneurons constitute an extremely diverse population of cells organized in a well-defined topology of precisely interconnected cells. They play a crucial role regulating inhibitory-excitatory balance in brain circuits, gating sensory perception, and regulating spike timing to brain oscillations during distinct behaviors. Dysfunctions in the establishment of proper inhibitory circuits have been associated to several brain disorders such as autism, epilepsy, and schizophrenia. In the rodent adult cortex, inhibitory neurons are generated during the second gestational week from distinct progenitor lineages located in restricted domains of the ventral telencephalon. However, only recently, studies have revealed some of the mechanisms generating the heterogeneity of neuronal subtypes and their modes of integration in brain networks. Here we will discuss some the events involved in the production of cortical GABAergic neuron diversity with focus on the interaction between intrinsically driven genetic programs and environmental signals during development.

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Germany 1 1%
Unknown 92 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 19%
Researcher 17 18%
Student > Master 14 15%
Student > Bachelor 11 12%
Other 6 6%
Other 13 14%
Unknown 16 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 28%
Neuroscience 26 27%
Biochemistry, Genetics and Molecular Biology 7 7%
Medicine and Dentistry 6 6%
Social Sciences 2 2%
Other 5 5%
Unknown 22 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2019.
All research outputs
#15,074,573
of 25,622,179 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,996
of 4,739 outputs
Outputs of similar age
#135,636
of 279,851 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#54
of 109 outputs
Altmetric has tracked 25,622,179 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,739 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,851 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 109 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.