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Attention Score in Context
| Title |
The dependence of neuronal encoding efficiency on Hebbian plasticity and homeostatic regulation of neurotransmitter release
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, April 2015
|
| DOI | 10.3389/fncel.2015.00164 |
| Pubmed ID | |
| Authors |
Faramarz Faghihi, Ahmed A. Moustafa |
| Abstract |
Synapses act as information filters by different molecular mechanisms including retrograde messenger that affect neuronal spiking activity. One of the well-known effects of retrograde messenger in presynaptic neurons is a change of the probability of neurotransmitter release. Hebbian learning describe a strengthening of a synapse between a presynaptic input onto a postsynaptic neuron when both pre- and postsynaptic neurons are coactive. In this work, a theory of homeostatic regulation of neurotransmitter release by retrograde messenger and Hebbian plasticity in neuronal encoding is presented. Encoding efficiency was measured for different synaptic conditions. In order to gain high encoding efficiency, the spiking pattern of a neuron should be dependent on the intensity of the input and show low levels of noise. In this work, we represent spiking trains as zeros and ones (corresponding to non-spike or spike in a time bin, respectively) as words with length equal to three. Then the frequency of each word (here eight words) is measured using spiking trains. These frequencies are used to measure neuronal efficiency in different conditions and for different parameter values. Results show that neurons that have synapses acting as band-pass filters show the highest efficiency to encode their input when both Hebbian mechanism and homeostatic regulation of neurotransmitter release exist in synapses. Specifically, the integration of homeostatic regulation of feedback inhibition with Hebbian mechanism and homeostatic regulation of neurotransmitter release in the synapses leads to even higher efficiency when high stimulus intensity is presented to the neurons. However, neurons with synapses acting as high-pass filters show no remarkable increase in encoding efficiency for all simulated synaptic plasticity mechanisms. This study demonstrates the importance of cooperation of Hebbian mechanism with regulation of neurotransmitter release induced by rapid diffused retrograde messenger in neurons with synapses as low and band-pass filters to obtain high encoding efficiency in different environmental and physiological conditions. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 6% |
| United Kingdom | 1 | 3% |
| Australia | 1 | 3% |
| Brazil | 1 | 3% |
| Unknown | 27 | 84% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 31% |
| Researcher | 5 | 16% |
| Professor > Associate Professor | 3 | 9% |
| Student > Doctoral Student | 3 | 9% |
| Student > Bachelor | 2 | 6% |
| Other | 7 | 22% |
| Unknown | 2 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 12 | 38% |
| Agricultural and Biological Sciences | 9 | 28% |
| Social Sciences | 3 | 9% |
| Medicine and Dentistry | 2 | 6% |
| Biochemistry, Genetics and Molecular Biology | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 2 | 6% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2015.
All research outputs
#15,333,503
of 22,805,349 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,664
of 4,240 outputs
Outputs of similar age
#157,007
of 264,510 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#83
of 110 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,240 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,510 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.