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Delirium from the gliocentric perspective

Overview of attention for article published in Frontiers in Cellular Neuroscience, May 2015
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  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Average Attention Score compared to outputs of the same age and source

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Title
Delirium from the gliocentric perspective
Published in
Frontiers in Cellular Neuroscience, May 2015
DOI 10.3389/fncel.2015.00171
Pubmed ID
Authors

Adonis Sfera, Carolina Osorio, Amy I. Price, Roberto Gradini, Michael Cummings

Abstract

Delirium is an acute state marked by disturbances in cognition, attention, memory, perception, and sleep-wake cycle which is common in elderly. Others have shown an association between delirium and increased mortality, length of hospitalization, cost, and discharge to extended stay facilities. Until recently it was not known that after an episode of delirium in elderly, there is a 63% probability of developing dementia at 48 months compared to 8% in patients without delirium. Currently there are no preventive therapies for delirium, thus elucidation of cellular and molecular underpinnings of this condition may lead to the development of early interventions and thus prevent permanent cognitive damage. In this article we make the case for the role of glia in the pathophysiology of delirium and describe an astrocyte-dependent central and peripheral cholinergic anti-inflammatory shield which may be disabled by astrocytic pathology, leading to neuroinflammation and delirium. We also touch on the role of glia in information processing and neuroimaging.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 60 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 20%
Student > Master 10 16%
Student > Postgraduate 8 13%
Researcher 5 8%
Student > Bachelor 3 5%
Other 8 13%
Unknown 15 25%
Readers by discipline Count As %
Medicine and Dentistry 13 21%
Neuroscience 12 20%
Nursing and Health Professions 5 8%
Psychology 5 8%
Agricultural and Biological Sciences 4 7%
Other 9 15%
Unknown 13 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2021.
All research outputs
#14,932,281
of 25,402,889 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,978
of 4,706 outputs
Outputs of similar age
#134,285
of 279,047 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#56
of 110 outputs
Altmetric has tracked 25,402,889 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,706 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,047 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.