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The contribution of interindividual factors to variability of response in transcranial direct current stimulation studies

Overview of attention for article published in Frontiers in Cellular Neuroscience, May 2015
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  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Average Attention Score compared to outputs of the same age and source

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Title
The contribution of interindividual factors to variability of response in transcranial direct current stimulation studies
Published in
Frontiers in Cellular Neuroscience, May 2015
DOI 10.3389/fncel.2015.00181
Pubmed ID
Authors

Lucia M. Li, Kazumasa Uehara, Takashi Hanakawa

Abstract

There has been an explosion of research using transcranial direct current stimulation (tDCS) for investigating and modulating human cognitive and motor function in healthy populations. It has also been used in many studies seeking to improve deficits in disease populations. With the slew of studies reporting "promising results" for everything from motor recovery after stroke to boosting memory function, one could be easily seduced by the idea of tDCS being the next panacea for all neurological ills. However, huge variability exists in the reported effects of tDCS, with great variability in the effect sizes and even contradictory results reported. In this review, we consider the interindividual factors that may contribute to this variability. In particular, we discuss the importance of baseline neuronal state and features, anatomy, age and the inherent variability in the injured brain. We additionally consider how interindividual variability affects the results of motor-evoked potential (MEP) testing with transcranial magnetic stimulation (TMS), which, in turn, can lead to apparent variability in response to tDCS in motor studies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 539 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 2 <1%
Netherlands 1 <1%
Germany 1 <1%
China 1 <1%
Spain 1 <1%
Unknown 533 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 109 20%
Researcher 76 14%
Student > Master 70 13%
Student > Bachelor 52 10%
Student > Doctoral Student 37 7%
Other 87 16%
Unknown 108 20%
Readers by discipline Count As %
Neuroscience 123 23%
Psychology 107 20%
Medicine and Dentistry 68 13%
Engineering 24 4%
Agricultural and Biological Sciences 18 3%
Other 53 10%
Unknown 146 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 May 2015.
All research outputs
#13,086,082
of 22,805,349 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,697
of 4,241 outputs
Outputs of similar age
#121,709
of 264,481 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#54
of 110 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,241 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,481 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.