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Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update

Overview of attention for article published in Frontiers in Cellular Neuroscience, June 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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1 blog
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138 Mendeley
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Title
Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update
Published in
Frontiers in Cellular Neuroscience, June 2015
DOI 10.3389/fncel.2015.00212
Pubmed ID
Authors

Venkata Subba Rao Atluri, Melissa Hidalgo, Thangavel Samikkannu, Kesava Rao Venkata Kurapati, Rahul Dev Jayant, Vidya Sagar, Madhavan P. N. Nair

Abstract

The blood-brain barrier (BBB) is a diffusion barrier that has an important role in maintaining a precisely regulated microenvironment protecting the neural tissue from infectious agents and toxins in the circulating system. Compromised BBB integrity plays a major role in the pathogenesis of retroviral associated neurological diseases. Human Immunodeficiency Virus (HIV) infection in the Central Nervous System (CNS) is an early event even before the serodiagnosis for HIV positivity or the initiation of antiretroviral therapy (ART), resulting in neurological complications in many of the infected patients. Macrophages, microglia and astrocytes (in low levels) are the most productively/latently infected cell types within the CNS. In this brief review, we have discussed about the effect of HIV infection and viral proteins on the integrity and function of BBB, which may contribute to the progression of HIV associated neurocognitive disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
France 1 <1%
Unknown 136 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 18%
Student > Master 21 15%
Student > Bachelor 17 12%
Researcher 14 10%
Student > Doctoral Student 7 5%
Other 19 14%
Unknown 35 25%
Readers by discipline Count As %
Medicine and Dentistry 21 15%
Biochemistry, Genetics and Molecular Biology 19 14%
Agricultural and Biological Sciences 13 9%
Immunology and Microbiology 12 9%
Pharmacology, Toxicology and Pharmaceutical Science 12 9%
Other 20 14%
Unknown 41 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2023.
All research outputs
#4,156,810
of 24,702,628 outputs
Outputs from Frontiers in Cellular Neuroscience
#878
of 4,584 outputs
Outputs of similar age
#49,985
of 271,551 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#26
of 110 outputs
Altmetric has tracked 24,702,628 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,584 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,551 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.