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Sympathoadrenergic modulation of hematopoiesis: a review of available evidence and of therapeutic perspectives

Overview of attention for article published in Frontiers in Cellular Neuroscience, August 2015
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  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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3 X users

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Title
Sympathoadrenergic modulation of hematopoiesis: a review of available evidence and of therapeutic perspectives
Published in
Frontiers in Cellular Neuroscience, August 2015
DOI 10.3389/fncel.2015.00302
Pubmed ID
Authors

Marco Cosentino, Franca Marino, Georges J. M. Maestroni

Abstract

Innervation of the bone marrow (BM) has been described more than one century ago, however the first in vivo evidence that sympathoadrenergic fibers have a role in hematopoiesis dates back to less than 25 years ago. Evidence has since increased showing that adrenergic nerves in the BM release noradrenaline and possibly also dopamine, which act on adrenoceptors and dopaminergic receptors (DR) expressed on hematopoietic cells and affect cell survival, proliferation, migration and engraftment ability. Remarkably, dysregulation of adrenergic fibers to the BM is associated with hematopoietic disturbances and myeloproliferative disease. Several adrenergic and dopaminergic agents are already in clinical use for non-hematological indications and with a usually favorable risk-benefit profile, and are therefore potential candidates for non-conventional modulation of hematopoiesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 1%
Unknown 80 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 19%
Student > Bachelor 15 19%
Student > Master 7 9%
Student > Doctoral Student 6 7%
Professor > Associate Professor 5 6%
Other 9 11%
Unknown 24 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 15%
Agricultural and Biological Sciences 9 11%
Medicine and Dentistry 8 10%
Neuroscience 7 9%
Immunology and Microbiology 4 5%
Other 13 16%
Unknown 28 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2022.
All research outputs
#14,435,683
of 23,122,481 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,223
of 4,285 outputs
Outputs of similar age
#137,034
of 264,821 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#58
of 131 outputs
Altmetric has tracked 23,122,481 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,285 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,821 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.