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On the possible role of stimulation duration for after-effects of transcranial alternating current stimulation

Overview of attention for article published in Frontiers in Cellular Neuroscience, August 2015
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Title
On the possible role of stimulation duration for after-effects of transcranial alternating current stimulation
Published in
Frontiers in Cellular Neuroscience, August 2015
DOI 10.3389/fncel.2015.00311
Pubmed ID
Authors

Daniel Strüber, Stefan Rach, Toralf Neuling, Christoph S. Herrmann

Abstract

Transcranial alternating current stimulation is a novel method that allows application of sinusoidal currents to modulate brain oscillations and cognitive processes. Studies in humans have demonstrated transcranial alternating current stimulation (tACS) after-effects following stimulation durations in the range of minutes. However, such after-effects are absent in animal studies using much shorter stimulation protocols in the range of seconds. Thus, stimulation duration might be a critical parameter for after-effects to occur. To test this hypothesis, we repeated a recent human tACS experiment with a short duration. We applied alpha tACS intermittently for 1 s duration while keeping other parameters identical. The results demonstrate that this very short intermittent protocol did not produce after-effects on amplitude or phase of the electroencephalogram. Since synaptic plasticity has been suggested as a possible mechanism for after-effects, our results indicate that a stimulation duration of 1 s is too short to induce synaptic plasticity. Future studies in animals are required that use extended stimulation durations to reveal the neuronal underpinnings. A better understanding of the mechanisms of tACS after-effects is crucial for potential clinical applications.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
France 1 <1%
Germany 1 <1%
Unknown 160 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 20%
Student > Master 28 17%
Researcher 25 15%
Student > Doctoral Student 15 9%
Student > Bachelor 12 7%
Other 22 13%
Unknown 29 18%
Readers by discipline Count As %
Psychology 45 28%
Neuroscience 39 24%
Medicine and Dentistry 13 8%
Agricultural and Biological Sciences 9 6%
Engineering 4 2%
Other 12 7%
Unknown 41 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2015.
All research outputs
#15,332,207
of 23,577,761 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,487
of 4,388 outputs
Outputs of similar age
#147,877
of 265,766 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#65
of 138 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,388 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,766 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.