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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Relevance of chronic stress and the two faces of microglia in Parkinson’s disease
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, August 2015
|
| DOI | 10.3389/fncel.2015.00312 |
| Pubmed ID | |
| Authors |
Antonio J. Herrera, Ana M. Espinosa-Oliva, Alejandro Carrillo-Jiménez, María J. Oliva-Martín, Juan García-Revilla, Alberto García-Quintanilla, Rocío M. de Pablos, José L. Venero |
| Abstract |
This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the inflammatory response of brain microglia and hence its potential involvement in Parkinson's disease (PD). The role of inflammation in PD has been reviewed extensively in the literature and it is supposed to play a key role in the course of the disease. Historically, GCs have been strongly associated as anti-inflammatory hormones. However, accumulating evidence from the peripheral and central nervous system have clearly revealed that, under specific conditions, GCs may promote brain inflammation including pro-inflammatory activation of microglia. We have summarized relevant data linking PD, neuroinflamamation and chronic stress. The timing and duration of stress response may be critical for delineating an immune response in the brain thus probably explain the dual role of GCs and/or chronic stress in different animal models of PD. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 1% |
| Unknown | 78 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 20% |
| Student > Bachelor | 14 | 18% |
| Researcher | 12 | 15% |
| Student > Master | 7 | 9% |
| Professor > Associate Professor | 5 | 6% |
| Other | 11 | 14% |
| Unknown | 14 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 19 | 24% |
| Agricultural and Biological Sciences | 11 | 14% |
| Medicine and Dentistry | 11 | 14% |
| Biochemistry, Genetics and Molecular Biology | 9 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 8% |
| Other | 8 | 10% |
| Unknown | 15 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2018.
All research outputs
#2,551,935
of 22,824,164 outputs
Outputs from Frontiers in Cellular Neuroscience
#407
of 4,244 outputs
Outputs of similar age
#34,519
of 264,379 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#11
of 138 outputs
Altmetric has tracked 22,824,164 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,244 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,379 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.