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Attention Score in Context
| Title |
Synaptic remodeling of neuronal circuits in early retinal degeneration
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, October 2015
|
| DOI | 10.3389/fncel.2015.00395 |
| Pubmed ID | |
| Authors |
Florentina Soto, Daniel Kerschensteiner |
| Abstract |
Photoreceptor degenerations are a major cause of blindness and among the most common forms of neurodegeneration in humans. Studies of mouse models revealed that synaptic dysfunction often precedes photoreceptor degeneration, and that abnormal synaptic input from photoreceptors to bipolar cells causes circuits in the inner retina to become hyperactive. Here, we provide a brief overview of frequently used mouse models of photoreceptor degenerations. We then discuss insights into circuit remodeling triggered by early synaptic dysfunction in the outer and hyperactivity in the inner retina. We discuss these insights in the context of other experimental manipulations of synaptic function and activity. Knowledge of the plasticity and early remodeling of retinal circuits will be critical for the design of successful vision rescue strategies. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 60 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 31% |
| Student > Ph. D. Student | 18 | 30% |
| Student > Master | 4 | 7% |
| Student > Doctoral Student | 3 | 5% |
| Student > Bachelor | 2 | 3% |
| Other | 7 | 11% |
| Unknown | 8 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 27 | 44% |
| Agricultural and Biological Sciences | 10 | 16% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Medicine and Dentistry | 4 | 7% |
| Chemistry | 2 | 3% |
| Other | 3 | 5% |
| Unknown | 11 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2023.
All research outputs
#3,776,855
of 23,243,271 outputs
Outputs from Frontiers in Cellular Neuroscience
#806
of 4,309 outputs
Outputs of similar age
#51,058
of 278,988 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#22
of 127 outputs
Altmetric has tracked 23,243,271 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,309 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,988 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 127 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.