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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Potassium Channels and Human Epileptic Phenotypes: An Updated Overview
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, March 2016
|
| DOI | 10.3389/fncel.2016.00081 |
| Pubmed ID | |
| Authors |
Chiara Villa, Romina Combi |
| Abstract |
Potassium (K(+)) channels are expressed in almost every cells and are ubiquitous in neuronal and glial cell membranes. These channels have been implicated in different disorders, in particular in epilepsy. K(+) channel diversity depends on the presence in the human genome of a large number of genes either encoding pore-forming or accessory subunits. More than 80 genes encoding the K(+) channels were cloned and they represent the largest group of ion channels regulating the electrical activity of cells in different tissues, including the brain. It is therefore not surprising that mutations in these genes lead to K(+) channels dysfunctions linked to inherited epilepsy in humans and non-human model animals. This article reviews genetic and molecular progresses in exploring the pathogenesis of different human epilepsies, with special emphasis on the role of K(+) channels in monogenic forms. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 181 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 181 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 19% |
| Researcher | 25 | 14% |
| Student > Bachelor | 17 | 9% |
| Student > Master | 16 | 9% |
| Other | 16 | 9% |
| Other | 26 | 14% |
| Unknown | 46 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 36 | 20% |
| Agricultural and Biological Sciences | 27 | 15% |
| Biochemistry, Genetics and Molecular Biology | 23 | 13% |
| Medicine and Dentistry | 21 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 5% |
| Other | 17 | 9% |
| Unknown | 48 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2016.
All research outputs
#20,317,110
of 22,858,915 outputs
Outputs from Frontiers in Cellular Neuroscience
#3,585
of 4,254 outputs
Outputs of similar age
#254,730
of 300,631 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#77
of 93 outputs
Altmetric has tracked 22,858,915 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,254 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,631 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.