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A Postsynaptic Role for Short-Term Neuronal Facilitation in Dendritic Spines

Overview of attention for article published in Frontiers in Cellular Neuroscience, September 2016
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Title
A Postsynaptic Role for Short-Term Neuronal Facilitation in Dendritic Spines
Published in
Frontiers in Cellular Neuroscience, September 2016
DOI 10.3389/fncel.2016.00224
Pubmed ID
Authors

Sunggu Yang, Mariton D. Santos, Cha-Min Tang, Jae Geun Kim, Sungchil Yang

Abstract

Synaptic plasticity is a fundamental component of information processing in the brain. Presynaptic facilitation in response to repetitive stimuli, often referred to as paired-pulse facilitation (PPF), is a dominant form of short-term synaptic plasticity. Recently, an additional cellular mechanism for short-term facilitation, short-term postsynaptic plasticity (STPP), has been proposed. While a dendritic mechanism was described in hippocampus, its expression has not yet been demonstrated at the levels of the spine. Furthermore, it is unknown whether the mechanism can be expressed in other brain regions, such as sensory cortex. Here, we demonstrated that a postsynaptic response can be facilitated by prior spine excitation in both hippocampal and cortical neurons, using 3D digital holography and two-photon calcium imaging. The coordinated action of pre- and post-synaptic plasticity may provide a more thorough account of information processing in the brain.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 4%
Unknown 25 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 23%
Student > Ph. D. Student 5 19%
Researcher 4 15%
Student > Master 3 12%
Student > Doctoral Student 2 8%
Other 3 12%
Unknown 3 12%
Readers by discipline Count As %
Neuroscience 9 35%
Agricultural and Biological Sciences 8 31%
Biochemistry, Genetics and Molecular Biology 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Linguistics 1 4%
Other 2 8%
Unknown 3 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 September 2016.
All research outputs
#20,344,065
of 22,890,496 outputs
Outputs from Frontiers in Cellular Neuroscience
#3,585
of 4,256 outputs
Outputs of similar age
#279,615
of 322,482 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#40
of 62 outputs
Altmetric has tracked 22,890,496 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,256 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.