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Attention Score in Context
| Title |
Two-Photon Holographic Stimulation of ReaChR
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, October 2016
|
| DOI | 10.3389/fncel.2016.00234 |
| Pubmed ID | |
| Authors |
Emmanuelle Chaigneau, Emiliano Ronzitti, Marta A. Gajowa, Gilberto J. Soler-Llavina, Dimitrii Tanese, Anthony Y. B. Brureau, Eirini Papagiakoumou, Hongkui Zeng, Valentina Emiliani |
| Abstract |
Optogenetics provides a unique approach to remotely manipulate brain activity with light. Reaching the degree of spatiotemporal control necessary to dissect the role of individual cells in neuronal networks, some of which reside deep in the brain, requires joint progress in opsin engineering and light sculpting methods. Here we investigate for the first time two-photon stimulation of the red-shifted opsin ReaChR. We use two-photon (2P) holographic illumination to control the activation of individually chosen neurons expressing ReaChR in acute brain slices. We demonstrated reliable action potential generation in ReaChR-expressing neurons and studied holographic 2P-evoked spiking performances depending on illumination power and pulse width using an amplified laser and a standard femtosecond Ti:Sapphire oscillator laser. These findings provide detailed knowledge of ReaChR's behavior under 2P illumination paving the way for achieving in depth remote control of multiple cells with high spatiotemporal resolution deep within scattering tissue. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| France | 1 | <1% |
| Unknown | 117 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 25% |
| Researcher | 29 | 24% |
| Student > Master | 11 | 9% |
| Other | 7 | 6% |
| Student > Postgraduate | 6 | 5% |
| Other | 17 | 14% |
| Unknown | 20 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 29 | 24% |
| Agricultural and Biological Sciences | 25 | 21% |
| Physics and Astronomy | 23 | 19% |
| Engineering | 9 | 8% |
| Medicine and Dentistry | 6 | 5% |
| Other | 9 | 8% |
| Unknown | 19 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2020.
All research outputs
#14,864,294
of 22,893,031 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,402
of 4,257 outputs
Outputs of similar age
#189,718
of 316,298 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#29
of 67 outputs
Altmetric has tracked 22,893,031 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,257 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,298 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.