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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, February 2017
|
| DOI | 10.3389/fncel.2017.00023 |
| Pubmed ID | |
| Authors |
Martyna Podobinska, Ilona Szablowska-Gadomska, Justyna Augustyniak, Ioanna Sandvig, Axel Sandvig, Leonora Buzanska |
| Abstract |
The coordinated development of the nervous system requires fidelity in the expression of specific genes determining the different neural cell phenotypes. Stem cell fate decisions during neurodevelopment are strictly correlated with their epigenetic status. The epigenetic regulatory processes, such as DNA methylation and histone modifications discussed in this review article, may impact both neural stem cell (NSC) self-renewal and differentiation and thus play an important role in neurodevelopment. At the same time, stem cell decisions regarding fate commitment and differentiation are highly dependent on the temporospatial expression of specific genes contingent on the developmental stage of the nervous system. An interplay between the above, as well as basic cell processes, such as transcription regulation, DNA replication, cell cycle regulation and DNA repair therefore determine the accuracy and function of neuronal connections. This may significantly impact embryonic health and development as well as cognitive processes such as neuroplasticity and memory formation later in the adult. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Ireland | 1 | 25% |
| Switzerland | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Scientists | 1 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Korea, Republic of | 1 | <1% |
| United States | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 150 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 30 | 20% |
| Student > Ph. D. Student | 25 | 16% |
| Student > Bachelor | 21 | 14% |
| Researcher | 18 | 12% |
| Student > Doctoral Student | 7 | 5% |
| Other | 15 | 10% |
| Unknown | 37 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 34 | 22% |
| Agricultural and Biological Sciences | 31 | 20% |
| Neuroscience | 19 | 12% |
| Medicine and Dentistry | 13 | 8% |
| Chemistry | 3 | 2% |
| Other | 10 | 7% |
| Unknown | 43 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2017.
All research outputs
#14,863,214
of 24,072,790 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,169
of 4,473 outputs
Outputs of similar age
#228,897
of 426,790 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#41
of 96 outputs
Altmetric has tracked 24,072,790 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,473 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 426,790 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.