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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Rab GTPases: The Key Players in the Molecular Pathway of Parkinson’s Disease
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, March 2017
|
| DOI | 10.3389/fncel.2017.00081 |
| Pubmed ID | |
| Authors |
Meng-Meng Shi, Chang-He Shi, Yu-Ming Xu |
| Abstract |
Parkinson's disease (PD) is a progressive movement disorder with multiple non-motor symptoms. Although family genetic mutations only account for a small proportion of the cases, these mutations have provided several lines of evidence for the pathogenesis of PD, such as mitochondrial dysfunction, protein misfolding and aggregation, and the impaired autophagy-lysosome system. Recently, vesicle trafficking defect has emerged as a potential pathogenesis underlying this disease. Rab GTPases, serving as the core regulators of cellular membrane dynamics, may play an important role in the molecular pathway of PD through the complex interplay with numerous factors and PD-related genes. This might shed new light on the potential therapeutic strategies. In this review, we emphasize the important role of Rab GTPases in vesicle trafficking and summarize the interactions between Rab GTPases and different PD-related genes. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 33% |
| Mexico | 1 | 8% |
| Japan | 1 | 8% |
| United Kingdom | 1 | 8% |
| Brazil | 1 | 8% |
| Switzerland | 1 | 8% |
| Unknown | 3 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 50% |
| Scientists | 5 | 42% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 149 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Unknown | 148 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 21% |
| Student > Bachelor | 30 | 20% |
| Researcher | 19 | 13% |
| Student > Master | 14 | 9% |
| Student > Doctoral Student | 7 | 5% |
| Other | 21 | 14% |
| Unknown | 27 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 38 | 26% |
| Agricultural and Biological Sciences | 27 | 18% |
| Neuroscience | 24 | 16% |
| Medicine and Dentistry | 13 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 10 | 7% |
| Unknown | 34 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2017.
All research outputs
#2,028,061
of 24,072,790 outputs
Outputs from Frontiers in Cellular Neuroscience
#273
of 4,473 outputs
Outputs of similar age
#39,396
of 311,872 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#6
of 110 outputs
Altmetric has tracked 24,072,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,473 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,872 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.