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Targeting WNT Signaling for Multifaceted Glioblastoma Therapy

Overview of attention for article published in Frontiers in Cellular Neuroscience, October 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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6 X users
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1 patent

Citations

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84 Dimensions

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129 Mendeley
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Title
Targeting WNT Signaling for Multifaceted Glioblastoma Therapy
Published in
Frontiers in Cellular Neuroscience, October 2017
DOI 10.3389/fncel.2017.00318
Pubmed ID
Authors

Matthew McCord, Yoh-suke Mukouyama, Mark R. Gilbert, Sadhana Jackson

Abstract

The WNT signaling pathway has been of great interest to developmental biologists for decades and has more recently become a central topic for study in cancer biology. It is vital for cell growth and regulation of embryogenesis in many organ systems, particularly the CNS and its associated vasculature. We summarize the role of WNT in CNS development and describe how WNT signaling makes key contributions to malignant glioma stemness, invasiveness, therapeutic resistance, and angiogenesis. The role of WNT in these mechanisms, along with creation and maintainance of the blood-brain barrier (BBB), points to the potential of WNT as a multi-faceted target in malignant glioma therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 129 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 22 17%
Student > Ph. D. Student 20 16%
Student > Master 14 11%
Researcher 11 9%
Unspecified 6 5%
Other 17 13%
Unknown 39 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 39 30%
Agricultural and Biological Sciences 14 11%
Medicine and Dentistry 10 8%
Unspecified 6 5%
Engineering 4 3%
Other 15 12%
Unknown 41 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2023.
All research outputs
#5,295,136
of 24,884,310 outputs
Outputs from Frontiers in Cellular Neuroscience
#1,070
of 4,609 outputs
Outputs of similar age
#87,301
of 331,535 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#20
of 114 outputs
Altmetric has tracked 24,884,310 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,609 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,535 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.