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The Role of L-type Calcium Channels in Olfactory Learning and Its Modulation by Norepinephrine

Overview of attention for article published in Frontiers in Cellular Neuroscience, December 2017
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Title
The Role of L-type Calcium Channels in Olfactory Learning and Its Modulation by Norepinephrine
Published in
Frontiers in Cellular Neuroscience, December 2017
DOI 10.3389/fncel.2017.00394
Pubmed ID
Authors

Abhinaba Ghosh, Samantha J. Carew, Xihua Chen, Qi Yuan

Abstract

L type calcium channels (LTCCs) are prevalent in different systems and hold immense importance for maintaining/performing selective functions. In the nervous system, CaV1.2 and CaV1.3 are emerging as critical modulators of neuronal functions. Although the general role of these calcium channels in modulating synaptic plasticity and memory has been explored, their role in olfactory learning is not well understood. In this review article we first discuss the role of LTCCs in olfactory learning especially focusing on early odor preference learning in neonate rodents, presenting evidence that while NMDARs initiate stimulus-specific learning, LTCCs promote protein-synthesis dependent long-term memory (LTM). Norepinephrine (NE) release from the locus coeruleus (LC) is essential for early olfactory learning, thus noradrenergic modulation of LTCC function and its implication in olfactory learning is discussed here. We then address the differential roles of LTCCs in adult learning and learning in aged animals.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 29%
Student > Master 3 21%
Student > Bachelor 2 14%
Student > Ph. D. Student 2 14%
Student > Doctoral Student 1 7%
Other 1 7%
Unknown 1 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 29%
Psychology 3 21%
Business, Management and Accounting 1 7%
Nursing and Health Professions 1 7%
Biochemistry, Genetics and Molecular Biology 1 7%
Other 3 21%
Unknown 1 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2017.
All research outputs
#14,087,536
of 23,012,811 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,041
of 4,263 outputs
Outputs of similar age
#230,036
of 439,935 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#41
of 109 outputs
Altmetric has tracked 23,012,811 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,263 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,935 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 109 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.