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Laminar-dependent effects of cortical state on auditory cortical spontaneous activity

Overview of attention for article published in Frontiers in Neural Circuits, January 2012
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Title
Laminar-dependent effects of cortical state on auditory cortical spontaneous activity
Published in
Frontiers in Neural Circuits, January 2012
DOI 10.3389/fncir.2012.00109
Pubmed ID
Authors

Shuzo Sakata, Kenneth D. Harris

Abstract

Cortical circuits spontaneously generate coordinated activity even in the absence of external inputs. The character of this activity depends on cortical state. We investigated how state affects the organization of spontaneous activity across layers of rat auditory cortex in vivo, using juxtacellular recording of morphologically identified neurons and large-scale electrophysiological recordings. Superficial pyramidal cells (PCs) and putative fast-spiking interneurons (FSs) were consistently suppressed during cortical desynchronization. PCs in deep layers showed heterogeneous responses to desynchronization, with some cells showing increased rates, typically large tufted PCs of high baseline firing rate, but not FSs. Consistent results were found between desynchronization occurring spontaneously in unanesthetized animals, and desynchronization evoked by electrical stimulation of the pedunculopontine tegmental (PPT) nucleus under urethane anesthesia. We hypothesize that reduction in superficial layer firing may enhance the brain's extraction of behaviorally relevant signals from noisy brain activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 3 2%
United States 3 2%
Germany 2 1%
United Kingdom 2 1%
Italy 1 <1%
China 1 <1%
Belarus 1 <1%
Unknown 148 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 52 32%
Researcher 45 28%
Student > Master 12 7%
Professor > Associate Professor 9 6%
Student > Doctoral Student 7 4%
Other 19 12%
Unknown 17 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 56 35%
Neuroscience 53 33%
Medicine and Dentistry 10 6%
Physics and Astronomy 9 6%
Engineering 6 4%
Other 9 6%
Unknown 18 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2013.
All research outputs
#13,174,456
of 23,573,357 outputs
Outputs from Frontiers in Neural Circuits
#500
of 1,243 outputs
Outputs of similar age
#145,513
of 247,793 outputs
Outputs of similar age from Frontiers in Neural Circuits
#15
of 73 outputs
Altmetric has tracked 23,573,357 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,243 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,793 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.